Diisopropyl-carbamic acid (Z)-(3R,4S,5R,6S)-4,7-dihydroxy-3,5-dimethyl-6-triisopropylsilanyloxy-hept-1-enyl ester

Base Information

• Chemical Name: Diisopropyl-carbamic acid (Z)-(3R,4S,5R,6S)-4,7-dihydroxy-3,5-dimethyl-6-triisopropylsilanyloxy-hept-1-enyl ester
• CAS No.: 218167-41-0
• Molecular Formula: C₂₅H₅₁NO₅Si
• Molecular Weight: 473.769

Synonyms:Diisopropyl-carbamic acid (Z)-(3R,4S,5R,6S)-4,7-dihydroxy-3,5-dimethyl-6-triisopropylsilanyloxy-hept-1-enyl ester

Chemical Property of Diisopropyl-carbamic acid (Z)-(3R,4S,5R,6S)-4,7-dihydroxy-3,5-dimethyl-6-triisopropylsilanyloxy-hept-1-enyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Diisopropyl-carbamic acid (Z)-(3R,4S,5R,6S)-4,7-dihydroxy-3,5-dimethyl-6-triisopropylsilanyloxy-hept-1-enyl ester

There total 1 articles about Diisopropyl-carbamic acid (Z)-(3R,4S,5R,6S)-4,7-dihydroxy-3,5-dimethyl-6-triisopropylsilanyloxy-hept-1-enyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

triisopropylsilyl trifluoromethanesulfonate (80522-42-5) → Diisopropyl-carbamic acid (Z)-(3R,4S,5R,6S)-4,7-dihydroxy-3,5-dimethyl-6-triisopropylsilanyloxy-hept-1-enyl ester (218167-41-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 75 percent / CH₂Cl₂ / 2.5 h / 20 °C

2: 87 percent / DIBAL-H / CH₂Cl₂ / 1.5 h / -78 °C

3: 1.) TMEDA, n-BuLi, Ti(O-i-Pr)4 / 1.) Et₂O, hexane, -78 deg C, 30 min; -78 deg C, 30 min, 2.) Et₂O, hexane, 0 deg C, 4 h

With titanium(IV) isopropylate; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; diisobutylaluminium hydride; In dichloromethane;

DOI:10.1055/s-1998-1872

Reference yield:

Diisopropyl-carbamic acid (Z)-(3R,4S,5R,6S)-4,7-dihydroxy-3,5-dimethyl-6-triisopropylsilanyloxy-hept-1-enyl ester (218167-41-0) → C49H49N5O15

Guidance literature:

Multi-step reaction with 3 steps

1: 78 percent / Bu₄NF / tetrahydrofuran / 4 h / 20 °C

2: 80 percent / pyridine

3: 80 percent / pyridine

With pyridine; tetrabutyl ammonium fluoride; In tetrahydrofuran;

DOI:10.1055/s-1998-1872

Reference yield:

Diisopropyl-carbamic acid (Z)-(3R,4S,5R,6S)-4,7-dihydroxy-3,5-dimethyl-6-triisopropylsilanyloxy-hept-1-enyl ester (218167-41-0) → Diisopropyl-carbamic acid (Z)-(3R,4S,5R,6S)-4,6-dihydroxy-3,5-dimethyl-7-trityloxy-hept-1-enyl ester (218167-51-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / Bu₄NF / tetrahydrofuran / 4 h / 20 °C

2: 80 percent / pyridine

With pyridine; tetrabutyl ammonium fluoride; In tetrahydrofuran;

DOI:10.1055/s-1998-1872

upstream raw materials:

triisopropylsilyl trifluoromethanesulfonate

Downstream raw materials:

Diisopropyl-carbamic acid (Z)-(3R,4S,5R,6S)-4,6-dihydroxy-3,5-dimethyl-7-trityloxy-hept-1-enyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 218167-41-0 Diisopropyl-carbamic acid (Z)-(3R,4S,5R,6S)-4,7-dihydroxy-3,5-dimethyl-6-triisopropylsilanyloxy-hept-1-enyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send