1-Butyl-N,N-dimethyl-4-(((2-(triethylsilyl)-1H-indol-3-yl)methoxy)methyl)cyclohexanamine

Base Information

• Chemical Name: 1-Butyl-N,N-dimethyl-4-(((2-(triethylsilyl)-1H-indol-3-yl)methoxy)methyl)cyclohexanamine
• CAS No.: 1184953-16-9
• Molecular Formula: C₂₈H₄₈N₂OSi
• Molecular Weight: 456.787

Synonyms:1-Butyl-N,N-dimethyl-4-(((2-(triethylsilyl)-1H-indol-3-yl)methoxy)methyl)cyclohexanamine

Chemical Property of 1-Butyl-N,N-dimethyl-4-(((2-(triethylsilyl)-1H-indol-3-yl)methoxy)methyl)cyclohexanamine

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Technology Process of 1-Butyl-N,N-dimethyl-4-(((2-(triethylsilyl)-1H-indol-3-yl)methoxy)methyl)cyclohexanamine

There total 1 articles about 1-Butyl-N,N-dimethyl-4-(((2-(triethylsilyl)-1H-indol-3-yl)methoxy)methyl)cyclohexanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

1-Butyl-N,N-dimethyl-4-((3-(triethylsilyl)prop-2-ynyloxy)methyl)cyclohexanamine (1184953-63-6) + 2-iodophenylamine (615-43-0) → 1-Butyl-N,N-dimethyl-4-(((2-(triethylsilyl)-1H-indol-3-yl)methoxy)methyl)cyclohexanamine (1184953-16-9)

Guidance literature:

With sodium carbonate; In N,N-dimethyl-formamide; at 100 ℃;

Reference yield: 67.0%

1-Butyl-N,N-dimethyl-4-(((2-(triethylsilyl)-1H-indol-3-yl)methoxy)methyl)cyclohexanamine (1184953-16-9) → 4-(((1H-Indol-3-yl)methoxy)methyl)-1-butyl-N,N-dimethylcyclohexanamine (1184953-17-0)

Guidance literature:

With trimethyl(benzyl)ammonium fluoride; In tetrahydrofuran; for 1.5h; Molecular sieve; Reflux;

upstream raw materials:

1-Butyl-N,N-dimethyl-4-((3-(triethylsilyl)prop-2-ynyloxy)methyl)cyclohexanamine

2-iodophenylamine

Downstream raw materials:

4-(((1H-Indol-3-yl)methoxy)methyl)-1-butyl-N,N-dimethylcyclohexanamine

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