3-Amino-N-phenylthiophene-2-carboxamide

Base Information

Chemical Name:3-Amino-N-phenylthiophene-2-carboxamide
CAS No.:147123-49-7
Molecular Formula:C₁₁H₁₀N₂OS
Molecular Weight:218.279
Hs Code.:
DSSTox Substance ID:DTXSID101281630

Synonyms:3-Amino-N-phenylthiophene-2-carboxamide;147123-49-7;SCHEMBL1703428;HTLHTGAZBNSDIS-UHFFFAOYSA-N;DTXSID101281630;3-Amino-N-phenyl-2-thiophenecarboxamide

Suppliers and Price of 3-Amino-N-phenylthiophene-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-Amino-N-phenylthiophene-2-carboxamide

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:218.05138412
Heavy Atom Count:15
Complexity:229

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC(=O)C2=C(C=CS2)N

Technology Process of 3-Amino-N-phenylthiophene-2-carboxamide

There total 6 articles about 3-Amino-N-phenylthiophene-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1029280-25-8
(2-phenylcarbamoylthiophen-3-yl)carbamic acid tert-butyl ester

: 147123-49-7
3-amino-N-phenylthiophene-2-carboxamide

Guidance literature:: (2-phenylcarbamoylthiophen-3-yl)carbamic acid tert-butyl ester; With trifluoroacetic acid; In dichloromethane; for 1h;

With sodium hydrogencarbonate; In dichloromethane; water; Product distribution / selectivity;

Reference yield:

: 3-amino-2-thiophenecarbonyl chloride

: 62-53-3
aniline

: 147123-49-7
3-amino-N-phenylthiophene-2-carboxamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 2h;
DOI:10.1016/j.tetlet.2018.12.025

Reference yield:

: 55341-87-2
3-aminothiophene-2-carboxylic acid

: 62-53-3
aniline

: 147123-49-7
3-amino-N-phenylthiophene-2-carboxamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃;
DOI:10.1039/d0gc03613g