ethyl 6-<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>-2-methoxy-4-methyl-3-pyridinecarboxylate

Base Information

Chemical Name:ethyl 6-<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>-2-methoxy-4-methyl-3-pyridinecarboxylate
CAS No.:145222-84-0
Molecular Formula:C₂₇H₃₃NO₄Si
Molecular Weight:463.649
Hs Code.:

Synonyms:ethyl 6-<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>-2-methoxy-4-methyl-3-pyridinecarboxylate

Suppliers and Price of ethyl 6-<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>-2-methoxy-4-methyl-3-pyridinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 6-<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>-2-methoxy-4-methyl-3-pyridinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 6-<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>-2-methoxy-4-methyl-3-pyridinecarboxylate

There total 4 articles about ethyl 6-<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>-2-methoxy-4-methyl-3-pyridinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 145222-83-9
ethyl 6-(hydroxymethyl)-2-methoxy-4-methyl-3-pyridinecarboxylate

: 58479-61-1
tert-butylchlorodiphenylsilane

: 145222-84-0
ethyl 6-<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>-2-methoxy-4-methyl-3-pyridinecarboxylate

Guidance literature:: With dmap; In dichloromethane;
DOI:10.1021/ja00104a009

Reference yield:

: 112463-87-3
ethyl 2-methoxy-4,6-dimethyl-3-pyridinecarboxylate

: 145222-84-0
ethyl 6-<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>-2-methoxy-4-methyl-3-pyridinecarboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: NBS, AIBN / CCl₄ / 3 h / Heating; Irradiation

2: aq. AgNO₃ / tetrahydrofuran

3: NaBH₄ / ethanol / 1 h / 0 °C

4: 97 percent / DMAP / CH₂Cl₂

With dmap; sodium tetrahydroborate; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); silver nitrate; In tetrahydrofuran; tetrachloromethane; ethanol; dichloromethane;
DOI:10.1021/ja00104a009

Reference yield:

: 161321-62-6
6-Formyl-2-methoxy-4-methyl-nicotinic acid ethyl ester

: 145222-84-0
ethyl 6-<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>-2-methoxy-4-methyl-3-pyridinecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: NaBH₄ / ethanol / 1 h / 0 °C

2: 97 percent / DMAP / CH₂Cl₂

With dmap; sodium tetrahydroborate; In ethanol; dichloromethane;
DOI:10.1021/ja00104a009