methyl 4-(1,3-dioxo-6-(piperidin-1-yl)-1H-benz[de]isoquinolin-2(3H)-yl)benzoate

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Chemical Name:methyl 4-(1,3-dioxo-6-(piperidin-1-yl)-1H-benz[de]isoquinolin-2(3H)-yl)benzoate
CAS No.:1449749-78-3
Molecular Formula:C₂₅H₂₂N₂O₄
Molecular Weight:414.461
Hs Code.:

Synonyms:methyl 4-(1,3-dioxo-6-(piperidin-1-yl)-1H-benz[de]isoquinolin-2(3H)-yl)benzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl 4-(1,3-dioxo-6-(piperidin-1-yl)-1H-benz[de]isoquinolin-2(3H)-yl)benzoate

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Technology Process of methyl 4-(1,3-dioxo-6-(piperidin-1-yl)-1H-benz[de]isoquinolin-2(3H)-yl)benzoate

There total 1 articles about methyl 4-(1,3-dioxo-6-(piperidin-1-yl)-1H-benz[de]isoquinolin-2(3H)-yl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 87223-12-9
6-(piperidin-1-yl)-1H,3H-benzo[de]isochromene-1,3-dione

: 619-45-4
4-methoxycarbonyl aniline

: 1449749-78-3
methyl 4-(1,3-dioxo-6-(piperidin-1-yl)-1H-benz[de]isoquinolin-2(3H)-yl)benzoate

Guidance literature:: In 2-ethoxy-ethanol; for 24h; Reflux;
DOI:10.3762/bjoc.9.147

Reference yield: 69.0%

: 1449749-78-3
methyl 4-(1,3-dioxo-6-(piperidin-1-yl)-1H-benz[de]isoquinolin-2(3H)-yl)benzoate

: 4-(1,3-dioxo-6-(piperidin-1-yl)-1H-benzo[de]isoquinolin-2(3H)-yl)benzoic acid

Guidance literature:: methyl 4-(1,3-dioxo-6-(piperidin-1-yl)-1H-benz[de]isoquinolin-2(3H)-yl)benzoate; With sodium hydroxide; In water; at 80 ℃; for 18h;

With hydrogenchloride; In water; pH=Ca. 2;
DOI:10.3762/bjoc.9.147