(2,6/3,4,5)-2,6-di-O-benzyl-4-O-tert-butyldimethylsilyl-3,5-O-methylenepentahydroxycyclohexanone

Base Information

• Chemical Name: (2,6/3,4,5)-2,6-di-O-benzyl-4-O-tert-butyldimethylsilyl-3,5-O-methylenepentahydroxycyclohexanone
• CAS No.: 1191953-66-8
• Molecular Formula: C₂₇H₃₆O₆Si
• Molecular Weight: 484.665
• Mol file: 1191953-66-8.mol

Synonyms:(2,6/3,4,5)-2,6-di-O-benzyl-4-O-tert-butyldimethylsilyl-3,5-O-methylenepentahydroxycyclohexanone

Chemical Property of (2,6/3,4,5)-2,6-di-O-benzyl-4-O-tert-butyldimethylsilyl-3,5-O-methylenepentahydroxycyclohexanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2,6/3,4,5)-2,6-di-O-benzyl-4-O-tert-butyldimethylsilyl-3,5-O-methylenepentahydroxycyclohexanone

There total 1 articles about (2,6/3,4,5)-2,6-di-O-benzyl-4-O-tert-butyldimethylsilyl-3,5-O-methylenepentahydroxycyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

4,6-di-O-benzyl-2-O-tert-butyldimethylsilyl-1,3-O-methylene-myo-inositol (890124-53-5) → (2,6/3,4,5)-2,6-di-O-benzyl-4-O-tert-butyldimethylsilyl-3,5-O-methylenepentahydroxycyclohexanone (1191953-66-8)

Guidance literature:

With Dess-Martin periodane; In dichloromethane; at 0 - 20 ℃;

DOI:10.1016/j.bmc.2009.07.025

Reference yield: 99.0%

(2,6/3,4,5)-2,6-di-O-benzyl-4-O-tert-butyldimethylsilyl-3,5-O-methylenepentahydroxycyclohexanone (1191953-66-8) → 4,6-di-O-benzyl-2-O-tert-butyldimethylsilyl-1,3-O-methylene-neo-inositol (1191990-06-3)

Guidance literature:

With L-Selectride; In tetrahydrofuran; at -78 ℃; for 0.5h; stereoselective reaction;

DOI:10.1016/j.bmc.2009.07.025

upstream raw materials:

4,6-di-O-benzyl-2-O-tert-butyldimethylsilyl-1,3-O-methylene-myo-inositol

Downstream raw materials:

4,6-di-O-benzyl-2-O-tert-butyldimethylsilyl-1,3-O-methylene-neo-inositol