1,4-bis(3,5-dihydroxyphenyl)-2,3-diphenyl-9H-tribenzo[a,c,e]cycloheptene

Base Information

• Chemical Name: 1,4-bis(3,5-dihydroxyphenyl)-2,3-diphenyl-9H-tribenzo[a,c,e]cycloheptene
• CAS No.: 1393486-83-3
• Molecular Formula: C₄₃H₃₀O₄
• Molecular Weight: 610.709
• Mol file: 1393486-83-3.mol

Synonyms:1,4-bis(3,5-dihydroxyphenyl)-2,3-diphenyl-9H-tribenzo[a,c,e]cycloheptene

Chemical Property of 1,4-bis(3,5-dihydroxyphenyl)-2,3-diphenyl-9H-tribenzo[a,c,e]cycloheptene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4-bis(3,5-dihydroxyphenyl)-2,3-diphenyl-9H-tribenzo[a,c,e]cycloheptene

There total 2 articles about 1,4-bis(3,5-dihydroxyphenyl)-2,3-diphenyl-9H-tribenzo[a,c,e]cycloheptene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-bis(3,5-dimethoxyphenyl)propan-2-one (1391854-71-9) → 1,4-bis(3,5-dihydroxyphenyl)-2,3-diphenyl-9H-tribenzo[a,c,e]cycloheptene (1393486-83-3)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium hydroxide / ethanol / 0.5 h / Reflux

2: potassium tert-butylate / diethyl ether / 24 h / Inert atmosphere

3: boron tribromide / dichloromethane / 4 h / Inert atmosphere; Reflux

With potassium tert-butylate; boron tribromide; potassium hydroxide; In diethyl ether; ethanol; dichloromethane;

DOI:10.1021/ja3054354

Reference yield:

2,5-bis(3,5-dimethoxyphenyl)-3,4-diphenylcyclopentadienone (1393486-81-1) → 1,4-bis(3,5-dihydroxyphenyl)-2,3-diphenyl-9H-tribenzo[a,c,e]cycloheptene (1393486-83-3)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium tert-butylate / diethyl ether / 24 h / Inert atmosphere

2: boron tribromide / dichloromethane / 4 h / Inert atmosphere; Reflux

With potassium tert-butylate; boron tribromide; In diethyl ether; dichloromethane;

DOI:10.1021/ja3054354

Reference yield: 72.0%

1-bromo-hexane (111-25-1) + 1,4-bis(3,5-dihydroxyphenyl)-2,3-diphenyl-9H-tribenzo[a,c,e]cycloheptene (1393486-83-3) → 1,4-bis(3,5-dihexyloxyphenyl)-2,3-diphenyl-9H-tribenzo[a,c,e]cycloheptene (1393486-84-4)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 85 ℃;

DOI:10.1021/ja3054354

upstream raw materials:

1,3-bis(3,5-dimethoxyphenyl)propan-2-one

2,5-bis(3,5-dimethoxyphenyl)-3,4-diphenylcyclopentadienone

Downstream raw materials:

1,4-bis(3,5-dihexyloxyphenyl)-2,3-diphenyl-9H-tribenzo[a,c,e]cycloheptene