4-Bromo-benzoic acid (E)-(1S,4R)-2,4-dimethyl-1-((R)-1-methyl-2-oxo-butyl)-hept-2-enyl ester

Base Information

• Chemical Name: 4-Bromo-benzoic acid (E)-(1S,4R)-2,4-dimethyl-1-((R)-1-methyl-2-oxo-butyl)-hept-2-enyl ester
• CAS No.: 139964-88-8
• Molecular Formula: C₂₁H₂₉BrO₃
• Molecular Weight: 409.363
• Mol file: 139964-88-8.mol

Synonyms:4-Bromo-benzoic acid (E)-(1S,4R)-2,4-dimethyl-1-((R)-1-methyl-2-oxo-butyl)-hept-2-enyl ester

Chemical Property of 4-Bromo-benzoic acid (E)-(1S,4R)-2,4-dimethyl-1-((R)-1-methyl-2-oxo-butyl)-hept-2-enyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Bromo-benzoic acid (E)-(1S,4R)-2,4-dimethyl-1-((R)-1-methyl-2-oxo-butyl)-hept-2-enyl ester

There total 3 articles about 4-Bromo-benzoic acid (E)-(1S,4R)-2,4-dimethyl-1-((R)-1-methyl-2-oxo-butyl)-hept-2-enyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

(E)-(4R,5S,8R)-5-Hydroxy-4,6,8-trimethyl-undec-6-en-3-one (139964-87-7) + 4-chlorobenzoyl chloride (586-75-4) → 4-Bromo-benzoic acid (E)-(1S,4R)-2,4-dimethyl-1-((R)-1-methyl-2-oxo-butyl)-hept-2-enyl ester (139964-88-8)

Guidance literature:

With pyridine; In dichloromethane;

DOI:10.1016/S0040-4039(00)93961-3

Reference yield:

(2E,4R)-2,4-dimethylheptenal (105311-41-9) → 4-Bromo-benzoic acid (E)-(1S,4R)-2,4-dimethyl-1-((R)-1-methyl-2-oxo-butyl)-hept-2-enyl ester (139964-88-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) LDA / 1.) THF, -78 deg C

2: 75 percent / pyridine / CH₂Cl₂

With pyridine; lithium diisopropyl amide; In dichloromethane;

DOI:10.1016/S0040-4039(00)93961-3

Reference yield:

pentan-3-one (96-22-0) → 4-Bromo-benzoic acid (E)-(1S,4R)-2,4-dimethyl-1-((R)-1-methyl-2-oxo-butyl)-hept-2-enyl ester (139964-88-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) LDA / 1.) THF, -78 deg C

2: 75 percent / pyridine / CH₂Cl₂

With pyridine; lithium diisopropyl amide; In dichloromethane;

DOI:10.1016/S0040-4039(00)93961-3

upstream raw materials:

(E)-(4R,5S,8R)-5-Hydroxy-4,6,8-trimethyl-undec-6-en-3-one

4-chlorobenzoyl chloride

(2E,4R)-2,4-dimethylheptenal

pentan-3-one