tert-butyl (4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate

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Chemical Name:tert-butyl (4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate
CAS No.:1034769-89-5
Molecular Formula:C₂₄H₃₀BrN₅O₄
Molecular Weight:532.437
Hs Code.:

Synonyms:tert-butyl (4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate

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Chemical Property of tert-butyl (4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate

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Technology Process of tert-butyl (4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate

There total 1 articles about tert-butyl (4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 173341-02-1
N-(morpholin-2-ylmethyl)carbamic acid tert-butyl ester

: 370866-02-7
5-bromo-4-chloro-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridine

: 1034769-89-5
tert-butyl (4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate

Guidance literature:: With triethylamine; In butan-1-ol; at 160 ℃; for 3h; Microwave irradiation;

Reference yield: 62.0%

: 1034769-89-5
tert-butyl (4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate

: 98-80-6
phenylboronic acid

: 1034769-90-8
tert-butyl (4-(1-(4-methoxybenzyl)-5-phenyl-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate

Guidance literature:: With sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In water; acetonitrile; at 140 ℃; for 0.5h; Microwave irradiation;

Reference yield:

: 6165-69-1
Thien-3-ylboronic acid

: 1034769-89-5
tert-butyl (4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate

: 1174913-79-1
tert-butyl (4-(1-(4-methoxybenzyl)-5-(thiophen-3-yl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; sodium carbonate; In water; acetonitrile; at 140 ℃; for 0.5h; Inert atmosphere; Microwave irradiation;
DOI:10.1021/jm900314j