(6Z)-8-hydroxy-6-[hydroxy(2-chlorophenyl)methylene]-2,3-dimethyl-6,7-dihydroindeno[5,6-d]imidazol-5(3H)-one

Base Information

• Chemical Name: (6Z)-8-hydroxy-6-[hydroxy(2-chlorophenyl)methylene]-2,3-dimethyl-6,7-dihydroindeno[5,6-d]imidazol-5(3H)-one
• CAS No.: 1082553-08-9
• Molecular Formula: C₁₉H₁₅ClN₂O₃
• Molecular Weight: 354.793
• Mol file: 1082553-08-9.mol

Synonyms:(6Z)-8-hydroxy-6-[hydroxy(2-chlorophenyl)methylene]-2,3-dimethyl-6,7-dihydroindeno[5,6-d]imidazol-5(3H)-one

Chemical Property of (6Z)-8-hydroxy-6-[hydroxy(2-chlorophenyl)methylene]-2,3-dimethyl-6,7-dihydroindeno[5,6-d]imidazol-5(3H)-one

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (6Z)-8-hydroxy-6-[hydroxy(2-chlorophenyl)methylene]-2,3-dimethyl-6,7-dihydroindeno[5,6-d]imidazol-5(3H)-one

There total 1 articles about (6Z)-8-hydroxy-6-[hydroxy(2-chlorophenyl)methylene]-2,3-dimethyl-6,7-dihydroindeno[5,6-d]imidazol-5(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

6-[3-(2-chloro-phenyl)-3-oxo-propyl]-7-hydroxy-2,3-dimethyl-3H-benzoimidazole-5-carboxylic acid dimethylamide → 5-[(3R)-3-(2-chlorophenyl)-3-hydroxypropyl]-4-hydroxy-N,N,1,2-tetramethyl-1H-benzimidazole-6-carboxamide + (6Z)-8-hydroxy-6-[hydroxy(2-chlorophenyl)methylene]-2,3-dimethyl-6,7-dihydroindeno[5,6-d]imidazol-5(3H)-one (1082553-08-9) + 5-[(3S)-3-(2-chlorophenyl)-3-hydroxypropyl]-4-hydroxy-N,N,1,2-tetramethyl-1H-benzimidazole-6-carboxamide

Guidance literature:

With potassium tert-butylate; hydrogen; RuCl₂[(S)-Xyl-P-Phos][(S)-DAIPEN]; In isopropyl alcohol; tert-butyl alcohol; under 18751.9 Torr; Title compound not separated from byproducts.; Heating;

DOI:10.1016/j.tetasy.2008.08.022