tert-butyl 4-bromocinnamyl carbonate

Base Information

• Chemical Name: tert-butyl 4-bromocinnamyl carbonate
• CAS No.: 1246666-53-4
• Molecular Formula: C₁₄H₁₇BrO₃
• Molecular Weight: 313.191
• Mol file: 1246666-53-4.mol

Synonyms:tert-butyl 4-bromocinnamyl carbonate

Chemical Property of tert-butyl 4-bromocinnamyl carbonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of tert-butyl 4-bromocinnamyl carbonate

There total 1 articles about tert-butyl 4-bromocinnamyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

3-(4-bromophenyl)prop-2-en-1-ol (105515-33-1,130265-32-6) + di-tert-butyl dicarbonate (24424-99-5) → tert-butyl 4-bromocinnamyl carbonate (1246666-53-4)

Guidance literature:

With tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide; In dichloromethane; water; at 0 - 20 ℃;

DOI:10.1039/c5cc04085j

Reference yield: 99.0%

tert-butyl 4-bromocinnamyl carbonate (1246666-53-4) + 2-benzyl-4-phenylisoquinoline-1,3(2H,4H)-dione → (R,E)-2-benzyl-4-(3-(4-bromophenyl)allyl)-4-phenylisoquinoline-1,3(2H,4H)-dione

Guidance literature:

2-benzyl-4-phenylisoquinoline-1,3(2H,4H)-dione; With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium carbonate; (-)-1(R),2(R)-bis<2'-(diphenylphosphino)benzamido>-1,2-diphenylethane; In tetrahydrofuran; at -30 ℃; for 0.166667h; Inert atmosphere;

tert-butyl 4-bromocinnamyl carbonate; In tetrahydrofuran; at -30 ℃; for 4h; enantioselective reaction; Inert atmosphere;

DOI:10.1039/d0ob00765j

Reference yield: 98.0%

tert-butyl 4-bromocinnamyl carbonate (1246666-53-4) + C19H16N2O2 → C28H23BrN2O2

Guidance literature:

C₁₉H₁₆N₂O₂; With 1,4-diaza-bicyclo[2.2.2]octane; bis(1,5-cyclooctadiene)diiridium(I) dichloride; (3,5-dioxa-4-phospha-cyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)-bis-(1-phenyl-ethyl)-amine; In dichloromethane; at 50 ℃; for 0.0833333h; Inert atmosphere;

tert-butyl 4-bromocinnamyl carbonate; In dichloromethane; at 50 ℃; for 48h; enantioselective reaction; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.9b01934

upstream raw materials:

3-(4-bromophenyl)prop-2-en-1-ol

di-tert-butyl dicarbonate

Downstream raw materials:

C₁₆H₁₅BrO

C₁₆H₁₅BrO

3-(4-bromophenyl)-2-methyl-1-(trimethylsilyl)pent-4-en-1-one

(R)-5-((R)-1-(4-bromophenyl)allyl)-5-methyl-2-phenylthiazol-4(5H)-one