2-Bromo-1-(4-hydroxy-3-methylphenyl)ethan-1-one

Base Information

Chemical Name:2-Bromo-1-(4-hydroxy-3-methylphenyl)ethan-1-one
CAS No.:41877-17-2
Molecular Formula:C₉H₉BrO₂
Molecular Weight:229.073
Hs Code.:
DSSTox Substance ID:DTXSID501257744

Synonyms:41877-17-2;2-bromo-1-(4-hydroxy-3-methylphenyl)ethanone;2-bromo-1-(4-hydroxy-3-methylphenyl)ethan-1-one;SCHEMBL4700966;AMY6356;UDORKTOXFJWYDF-UHFFFAOYSA-N;DTXSID501257744;MFCD18391500;SY144190;2-Bromo-4'-hydroxy-3'-methylacetophenone;C15775;EN300-113735;2-bromo-1-(4-hydroxy-3-methyl-phenyl)-ethanone

Suppliers and Price of 2-Bromo-1-(4-hydroxy-3-methylphenyl)ethan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Bromo-1-(4-hydroxy-3-methylphenyl)ethanone 97%
25g
$ 1160.00

Crysdot
2-Bromo-1-(4-hydroxy-3-methylphenyl)ethanone 97%
5g
$ 360.00

Crysdot
2-Bromo-1-(4-hydroxy-3-methylphenyl)ethanone 97%
1g
$ 120.00

Crysdot
2-Bromo-1-(4-hydroxy-3-methylphenyl)ethanone 97%
10g
$ 580.00

Alichem
2-Bromo-4'-hydroxy-3'-methylacetophenone
250mg
$ 504.00

Alichem
2-Bromo-4'-hydroxy-3'-methylacetophenone
1g
$ 1534.70

Alichem
2-Bromo-4'-hydroxy-3'-methylacetophenone
500mg
$ 823.15

AK Scientific
2-Bromo-1-(4-hydroxy-3-methylphenyl)ethan-1-one
1g
$ 937.00

Total 4 raw suppliers

Chemical Property of 2-Bromo-1-(4-hydroxy-3-methylphenyl)ethan-1-one

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:227.97859
Heavy Atom Count:12
Complexity:170

Purity/Quality:

95% ^*data from raw suppliers

2-Bromo-1-(4-hydroxy-3-methylphenyl)ethanone 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C=CC(=C1)C(=O)CBr)O

Technology Process of 2-Bromo-1-(4-hydroxy-3-methylphenyl)ethan-1-one

There total 5 articles about 2-Bromo-1-(4-hydroxy-3-methylphenyl)ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.1%

: 876-02-8
4-hydroxy-3-methylphenyl methyl ketone

: 41877-17-2
2-bromo-1-(4-hydroxy-3-methylphenyl)ethan-1-one

Guidance literature:: With copper(I) bromide; In chloroform; ethyl acetate; for 5h; Reflux;

Reference yield:

: 95-48-7,77504-84-8
ortho-cresol

: 41877-17-2
2-bromo-1-(4-hydroxy-3-methylphenyl)ethan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / AlCl₃ / CS₂ / 1.) RT, 1 h, 2.) reflux, 12 h

2: 78 percent / dioxane dibromide / dioxane; diethyl ether / 2 h / Ambient temperature

With aluminium trichloride; 1,4-dioxane dibromide; In 1,4-dioxane; carbon disulfide; diethyl ether;
DOI:10.1021/jm00181a008

Reference yield:

: 533-18-6
2-methylphenyl acetate

: 41877-17-2
2-bromo-1-(4-hydroxy-3-methylphenyl)ethan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / AlCl₃ / nitromethane / 50 °C

2: 72 percent / CuBr₂ / CHCl₃; ethyl acetate / Heating

With aluminium trichloride; copper(ll) bromide; In nitromethane; chloroform; ethyl acetate; 1: Fries rearrangement;
DOI:10.1021/jo050050s