methyl-d3-magnesium iodide

Base Information

Chemical Name:methyl-d3-magnesium iodide
CAS No.:41251-37-0
Molecular Formula:CH₃IMg
Molecular Weight:169.221
Hs Code.:
European Community (EC) Number:803-764-0
DSSTox Substance ID:DTXSID70459001
Mol file:41251-37-0.mol

Synonyms:methyl-d3-magnesium iodide

Suppliers and Price of methyl-d3-magnesium iodide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl-d3-magnesiumIodide,~1.0?Mindiethylether
250ml
$ 2625.00

Sigma-Aldrich
Methyl-d3-magnesium iodide solution 1.0M in diethyl ether, 99 atom % D
100ml
$ 299.00

Medical Isotopes, Inc.
Methyl-d3-magnesium iodide solution
100 ml
$ 590.00

American Custom Chemicals Corporation
METHYL-D3-MAGNESIUM IODIDE SOLUTION 95.00%
100ML
$ 2549.09

Total 16 raw suppliers

Chemical Property of methyl-d3-magnesium iodide

Chemical Property:

Flash Point:?40?°F
Density:0.871?g/mL?at 25?°C
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:168.93182
Heavy Atom Count:3
Complexity:0

Purity/Quality:

98% ^*data from raw suppliers

Methyl-d3-magnesiumIodide,~1.0?Mindiethylether ^*data from reagent suppliers

Safty Information:

Pictogram(s): 3587273
Hazard Codes:F+,C,F
Statements: 12-14/15-22-66-67-34-19-11
Safety Statements: 16-36/37/39-43-45-26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:[CH3-].[Mg+2].[I-]
Isomeric SMILES:[2H][C-]([2H])[2H].[Mg+2].[I-]
Uses Methyl-d3-magnesium Iodide is used as a reagent in the synthesis of Anacetrapib-d3 (A637202); a labelled orally active and potent cholesterol ester transfer protein (CETP) inhibitor for the treatment of atherosclerosis, in particular dyslipidemia.

Technology Process of methyl-d3-magnesium iodide

There total 2 articles about methyl-d3-magnesium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 865-50-9
iodomethane-d3

: 41251-37-0
methyl-d3-magnesium iodide

Guidance literature:: With magnesium; In solid matrix; at -258.2 ℃;
DOI:10.1021/ja00530a028

Reference yield:

: 21524-04-9
pyridino tribromogold

: (dimethyl-d6)gold iodide dimer

: 41251-37-0
methyl-d3-magnesium iodide

Guidance literature:: In diethyl ether; react. of pyridino tribromogold with a 6-fold excess of freshly prepd. CD3MgI;
DOI:10.1021/om00112a033

Reference yield: 96.0%

: 932383-69-2
(1R,3aR,4S,7aR)-4-{1-[4-(tert-butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-cyclopropyl}ethyl-butyric acid methyl ester

: 41251-37-0
methyl-d3-magnesium iodide

: 932383-70-5
(1R,3aR,4S,7aR)-5-{1-[4-(tert-butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-cyclopropyl}-1,1,1-2-trideutero-2-trideuteromethyl-pentan-2-ol

Guidance literature:: (1R,3aR,4S,7aR)-4-{1-[4-(tert-butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-cyclopropyl}ethyl-butyric acid methyl ester; methyl-d3-magnesium iodide; In diethyl ether; at 0 - 20 ℃; for 1.5h;

With water; ammonium chloride; In diethyl ether; at 0 ℃;