O-Benzylstegobiol

Base Information

• Chemical Name: O-Benzylstegobiol
• CAS No.: 152428-80-3
• Molecular Formula: C₂₀H₂₈O₃
• Molecular Weight: 316.441
• Mol file: 152428-80-3.mol

Synonyms:O-Benzylstegobiol

Chemical Property of O-Benzylstegobiol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of O-Benzylstegobiol

There total 7 articles about O-Benzylstegobiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,3R,7S,8S)-8-Benzyloxy-2-(tert-butyl-dimethyl-silanyloxy)-3,5,7-trimethyl-decane-4,6-dione (152428-79-0) → O-Benzylstegobiol (152428-80-3)

Guidance literature:

With trifluoroacetic acid; In chloroform; at 25 ℃; for 0.5h; Yield given;

DOI:10.1021/jo00076a006

Reference yield:

(2S,3R,4S)-4-Benzyloxy-3-methyl-hexan-2-ol (152428-84-7) → O-Benzylstegobiol (152428-80-3)

Guidance literature:

Multi-step reaction with 6 steps

2: cyclohexene, CaCO₃ / Pd(OH)2 / ethanol

3: pyridinium dichromate, molecular sieves / CH₂Cl₂ / 3 h

5: pyridinium dichromate, molecular sieves / CH₂Cl₂ / 3 h

6: 25percent CF₃COOH / CHCl₃ / 0.5 h / 25 °C

With dipyridinium dichromate; molecular sieve; trifluoroacetic acid; calcium carbonate; cyclohexene; palladium dihydroxide; In ethanol; dichloromethane; chloroform;

DOI:10.1021/jo00076a006

Reference yield:

((1S,2S,3S)-3-Benzyloxy-1,2-dimethyl-pentyloxy)-tert-butyl-dimethyl-silane (152428-85-8) → O-Benzylstegobiol (152428-80-3)

Guidance literature:

Multi-step reaction with 5 steps

1: cyclohexene, CaCO₃ / Pd(OH)2 / ethanol

2: pyridinium dichromate, molecular sieves / CH₂Cl₂ / 3 h

4: pyridinium dichromate, molecular sieves / CH₂Cl₂ / 3 h

5: 25percent CF₃COOH / CHCl₃ / 0.5 h / 25 °C

With dipyridinium dichromate; molecular sieve; trifluoroacetic acid; calcium carbonate; cyclohexene; palladium dihydroxide; In ethanol; dichloromethane; chloroform;

DOI:10.1021/jo00076a006

upstream raw materials:

(2S,3R,7S,8S)-8-Benzyloxy-2-(tert-butyl-dimethyl-silanyloxy)-3,5,7-trimethyl-decane-4,6-dione

(4R,5S)-5-t-butyldimethylsilyloxy-4-methylhexan-3-one

(3S,4S,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-hexan-3-ol

(2S,3R,4S)-4-Benzyloxy-3-methyl-hexan-2-ol

Downstream raw materials:

(2S,3R)-2,3-dihydro-6-[(1'R)-1'-methyl-2'-oxobutyl]-2,3,5-trimethyl-4H-pyran-4-one