1-Phenylcyclopentanecarboxamide

Base Information

• Chemical Name: 1-Phenylcyclopentanecarboxamide
• CAS No.: 5296-89-9
• Molecular Formula: C12H15NO
• Molecular Weight: 189.257
• Hs Code.: 2924299090
• European Community (EC) Number: 661-297-6
• NSC Number: 135978
• UNII: W2VMT9MAU7
• DSSTox Substance ID: DTXSID30967430
• Nikkaji Number: J77.920B
• Wikidata: Q82950024
• Mol file: 5296-89-9.mol

Synonyms:1-phenylcyclopentanecarboxamide

Chemical Property of 1-Phenylcyclopentanecarboxamide

Chemical Property:

• Vapor Pressure: 8.49E-06mmHg at 25°C
• Boiling Point: 374.2°Cat760mmHg
• Flash Point: 180.1°C
• PSA: 43.09000
• Density: 1.114g/cm³
• LogP: 2.68400
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 189.115364102
• Heavy Atom Count: 14
• Complexity: 212

Purity/Quality:

1-Phenylcyclopentanecarboxamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CCC(C1)(C2=CC=CC=C2)C(=O)N

Technology Process of 1-Phenylcyclopentanecarboxamide

There total 7 articles about 1-Phenylcyclopentanecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1-phenyl-N-(quinolin-8-yl)cyclopentanecarboxamide (908520-36-5) → 1-phenylcyclopentane-1-carboxamide (5296-89-9)

Guidance literature:

1-phenyl-N-(quinolin-8-yl)cyclopentanecarboxamide; With ozone; In dichloromethane; at -78 ℃; Inert atmosphere;

With ammonium hydroxide; In tetrahydrofuran; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1002/chem.201604344

Reference yield: 79.2%

1-phenyl-1-cyclopentanecarbonitrile (77-57-6) → 1-phenylcyclopentane-1-carboxamide (5296-89-9)

Guidance literature:

With polyphosphoric acid; at 110 ℃; for 17h;

Reference yield:

1-phenylcyclopentanecarboxylic acid chloride (17380-62-0) → 1-phenylcyclopentane-1-carboxamide (5296-89-9)

Guidance literature:

upstream raw materials:

1-phenylcyclopentanecarboxylic acid chloride

1-phenyl-1-cyclopentanecarbonitrile

1-phenyl-N-(quinolin-8-yl)cyclopentanecarboxamide

1-phenyl-1-cyclopentanecarboxylic acid

Downstream raw materials:

Methyl-(1-phenylcyclopentyl)-carbamat

1-phenylcyclopentylamine

1-phenylcyclopentane-1-amine hydrochloride