2-(2-((4aS,5R)-1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl)ethyl)-N-methoxy-N-methylbenzamide

Base Information

Chemical Name:2-(2-((4aS,5R)-1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl)ethyl)-N-methoxy-N-methylbenzamide
CAS No.:1021539-42-3
Molecular Formula:C₂₈H₃₀FN₃O₃
Molecular Weight:475.563
Hs Code.:

Synonyms:2-(2-((4aS,5R)-1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl)ethyl)-N-methoxy-N-methylbenzamide

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Chemical Property of 2-(2-((4aS,5R)-1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl)ethyl)-N-methoxy-N-methylbenzamide

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Technology Process of 2-(2-((4aS,5R)-1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl)ethyl)-N-methoxy-N-methylbenzamide

There total 1 articles about 2-(2-((4aS,5R)-1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl)ethyl)-N-methoxy-N-methylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1021538-90-8
2-{2-[(4aS,5R)-1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl]ethyl}benzoic acid

: 73664-86-5
1,2-dimethylhydrazine hydrochloride

: 1021539-42-3
2-(2-((4aS,5R)-1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl)ethyl)-N-methoxy-N-methylbenzamide

Guidance literature:: With 4-methyl-morpholine; HATU; In N,N-dimethyl-formamide; for 72h;

Reference yield: 90.0%

: 1021539-42-3
2-(2-((4aS,5R)-1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl)ethyl)-N-methoxy-N-methylbenzamide

: 1021538-97-5
2-(2-((4aS,5R)-1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-yl)ethyl)benzaldehyde

Guidance literature:: 2-(2-((4aS,5R)-1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl)ethyl)-N-methoxy-N-methylbenzamide; With diisobutylaluminium hydride; In tetrahydrofuran; at -78 ℃; for 2h;

With water; Rochelle's salt; In tetrahydrofuran; at -78 - 20 ℃; for 1h;