(S)-2-[(S)-2-((S)-2-Amino-3-methyl-butyrylamino)-propionylamino]-3-(1H-indol-3-yl)-propionic acid phenyl ester; hydrochloride

Base Information

Chemical Name:(S)-2-[(S)-2-((S)-2-Amino-3-methyl-butyrylamino)-propionylamino]-3-(1H-indol-3-yl)-propionic acid phenyl ester; hydrochloride
CAS No.:80647-67-2
Molecular Formula:C₂₅H₃₀N₄O₄*ClH
Molecular Weight:486.999
Hs Code.:

Synonyms:(S)-2-[(S)-2-((S)-2-Amino-3-methyl-butyrylamino)-propionylamino]-3-(1H-indol-3-yl)-propionic acid phenyl ester; hydrochloride

Suppliers and Price of (S)-2-[(S)-2-((S)-2-Amino-3-methyl-butyrylamino)-propionylamino]-3-(1H-indol-3-yl)-propionic acid phenyl ester; hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-[(S)-2-((S)-2-Amino-3-methyl-butyrylamino)-propionylamino]-3-(1H-indol-3-yl)-propionic acid phenyl ester; hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-[(S)-2-((S)-2-Amino-3-methyl-butyrylamino)-propionylamino]-3-(1H-indol-3-yl)-propionic acid phenyl ester; hydrochloride

There total 3 articles about (S)-2-[(S)-2-((S)-2-Amino-3-methyl-butyrylamino)-propionylamino]-3-(1H-indol-3-yl)-propionic acid phenyl ester; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 80647-65-0
Z-Val-Ala-Trp-OPh

: 80647-67-2
(S)-2-[(S)-2-((S)-2-Amino-3-methyl-butyrylamino)-propionylamino]-3-(1H-indol-3-yl)-propionic acid phenyl ester; hydrochloride

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In N,N-dimethyl-formamide; for 3h;
DOI:10.1016/S0040-4020(01)98918-5

Reference yield:

: 75707-26-5
Z-Val-Ala-NHNH₂

: 80647-67-2
(S)-2-[(S)-2-((S)-2-Amino-3-methyl-butyrylamino)-propionylamino]-3-(1H-indol-3-yl)-propionic acid phenyl ester; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) HCl, tert-butyl nitrite, 2.) TEA / 1.) DMF, -20 deg C, 10 min, 2.) DMF, -20 deg C, 1 h, -10 deg C 70 h

2: 88 percent / H₂, HCl / Pd/C / dimethylformamide / 3 h

With hydrogenchloride; tert.-butylnitrite; TEA; hydrogen; palladium on activated charcoal; In N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)98918-5

Reference yield:

: 80647-61-6
(S)-phenyl 2-amino-3-(1H-indol-3-yl)propanoate hydrochloride

: 80647-67-2
(S)-2-[(S)-2-((S)-2-Amino-3-methyl-butyrylamino)-propionylamino]-3-(1H-indol-3-yl)-propionic acid phenyl ester; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) HCl, tert-butyl nitrite, 2.) TEA / 1.) DMF, -20 deg C, 10 min, 2.) DMF, -20 deg C, 1 h, -10 deg C 70 h

2: 88 percent / H₂, HCl / Pd/C / dimethylformamide / 3 h

With hydrogenchloride; tert.-butylnitrite; TEA; hydrogen; palladium on activated charcoal; In N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)98918-5