(R)-2-(1-hydroxybut-2-ylamino)-4-(4-bromobenzylamino)-8-isopropylpyrazolo[1,5-a]-1,3,5-triazine

Base Information

Chemical Name:(R)-2-(1-hydroxybut-2-ylamino)-4-(4-bromobenzylamino)-8-isopropylpyrazolo[1,5-a]-1,3,5-triazine
CAS No.:1244954-66-2
Molecular Formula:C₁₉H₂₅BrN₆O
Molecular Weight:433.351
Hs Code.:

Synonyms:(R)-2-(1-hydroxybut-2-ylamino)-4-(4-bromobenzylamino)-8-isopropylpyrazolo[1,5-a]-1,3,5-triazine

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Chemical Property of (R)-2-(1-hydroxybut-2-ylamino)-4-(4-bromobenzylamino)-8-isopropylpyrazolo[1,5-a]-1,3,5-triazine

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Technology Process of (R)-2-(1-hydroxybut-2-ylamino)-4-(4-bromobenzylamino)-8-isopropylpyrazolo[1,5-a]-1,3,5-triazine

There total 1 articles about (R)-2-(1-hydroxybut-2-ylamino)-4-(4-bromobenzylamino)-8-isopropylpyrazolo[1,5-a]-1,3,5-triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5856-63-3
(2R)-2-aminobutan-1-ol

: C₁₆H₁₈BrN₅OS

: 1244954-66-2
(R)-2-(1-hydroxybut-2-ylamino)-4-(4-bromobenzylamino)-8-isopropylpyrazolo[1,5-a]-1,3,5-triazine

Guidance literature:: at 140 ℃; for 24h;

Reference yield: 50.0%

: 6165-69-1
Thien-3-ylboronic acid

: 1244954-66-2
(R)-2-(1-hydroxybut-2-ylamino)-4-(4-bromobenzylamino)-8-isopropylpyrazolo[1,5-a]-1,3,5-triazine

: 1244954-75-3
(R)-2-(1-hydroxybut-2-ylamino)-8-isopropyl-4-[4-(thiophen-3-yl)benzylamino]pyrazolo[1,5-a]-1,3,5-triazine

Guidance literature:: With sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; at 140 ℃; Sealed tube;

Reference yield: 34.0%

: 1244954-66-2
(R)-2-(1-hydroxybut-2-ylamino)-4-(4-bromobenzylamino)-8-isopropylpyrazolo[1,5-a]-1,3,5-triazine

: 17997-47-6
2-tri-n-butylstannylpyridine

: 1244954-70-8
(R)-2-(1-hydroxybut-2-ylamino)-8-isopropyl-4-[4-(pyridin-2-yl)benzylamino]pyrazolo[1,5-a]-1,3,5-triazine

Guidance literature:: (R)-2-(1-hydroxybut-2-ylamino)-4-(4-bromobenzylamino)-8-isopropylpyrazolo[1,5-a]-1,3,5-triazine; 2-tri-n-butylstannylpyridine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; at 110 ℃; Sealed tube;

With sodium hydrogencarbonate; In toluene;