2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}-6-phenylhexanoic acid

Base Information

Chemical Name:2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}-6-phenylhexanoic acid
CAS No.:1316741-79-3
Molecular Formula:C₂₈H₂₇N₃O₄
Molecular Weight:469.54
Hs Code.:

Synonyms:2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}-6-phenylhexanoic acid

Suppliers and Price of 2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}-6-phenylhexanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}-6-phenylhexanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}-6-phenylhexanoic acid

There total 9 articles about 2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}-6-phenylhexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 1316742-36-5
2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}-6-phenylhexanoic acid ethyl ester

: 1316741-79-3
2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}-6-phenylhexanoic acid

Guidance literature:: With water; potassium hydroxide; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/jm200438b

Reference yield:

: 1316742-08-1
2-(RS)-amino-6-phenylhexanoic acid hydrochloride

: 1316741-79-3
2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}-6-phenylhexanoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogenchloride / 0.5 h

2: triethylamine / ethyl acetate / 4 h / Reflux

3: pyridine / dichloromethane / 0 - 20 °C

4: water; potassium hydroxide / tetrahydrofuran / 20 °C

With pyridine; hydrogenchloride; water; triethylamine; potassium hydroxide; In tetrahydrofuran; dichloromethane; ethyl acetate;
DOI:10.1021/jm200438b

Reference yield:

Indole-2-carboxylic acid: 1477-50-5,1228050-17-6
Indole-2-carboxylic acid

: 1316741-79-3
2-(RS)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}-6-phenylhexanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: phosphorus pentachloride; acetyl chloride / 3.5 h / 0 - 20 °C

2: pyridine / dichloromethane / 0 - 20 °C

3: water; potassium hydroxide / tetrahydrofuran / 20 °C

With pyridine; phosphorus pentachloride; water; acetyl chloride; potassium hydroxide; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm200438b