1-C-(2,3-di-O-benzyl-6-C-nitro-6-deoxy-α-D-ribo-hex-5-eno-furanosyl)acetone

Base Information

• Chemical Name: 1-C-(2,3-di-O-benzyl-6-C-nitro-6-deoxy-α-D-ribo-hex-5-eno-furanosyl)acetone
• CAS No.: 1168137-25-4
• Molecular Formula: C₂₃H₂₅NO₆
• Molecular Weight: 411.455
• Mol file: 1168137-25-4.mol

Synonyms:1-C-(2,3-di-O-benzyl-6-C-nitro-6-deoxy-α-D-ribo-hex-5-eno-furanosyl)acetone

Chemical Property of 1-C-(2,3-di-O-benzyl-6-C-nitro-6-deoxy-α-D-ribo-hex-5-eno-furanosyl)acetone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-C-(2,3-di-O-benzyl-6-C-nitro-6-deoxy-α-D-ribo-hex-5-eno-furanosyl)acetone

There total 1 articles about 1-C-(2,3-di-O-benzyl-6-C-nitro-6-deoxy-α-D-ribo-hex-5-eno-furanosyl)acetone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

C23H27NO7 (1168137-24-3) → 1-C-(2,3-di-O-benzyl-6-C-nitro-6-deoxy-α-D-ribo-hex-5-eno-furanosyl)acetone (1168137-25-4)

Guidance literature:

With methanesulfonyl chloride; triethylamine; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1016/j.carres.2009.03.007

Reference yield: 70.0%

1-C-(2,3-di-O-benzyl-6-C-nitro-6-deoxy-α-D-ribo-hex-5-eno-furanosyl)acetone (1168137-25-4) + cyclohexylamine (108-91-8,157973-60-9) → (1S,5R,6S,7R,8R,9S)-2-cyclohexyl-6,7-di-O-benzyl-8-hydroxy-3-methyl-9-nitro-2-azabicyclo[3.3.1]nonan-3-ene + (1R,2S,3R,4R,5S,6R)-1-acetylmethyl-5-cyclohexylamino-2,3-di-O-benzyl-4-hydroxy-6-nitrocyclohexane (1198581-83-7)

Guidance literature:

1-C-(2,3-di-O-benzyl-6-C-nitro-6-deoxy-α-D-ribo-hex-5-eno-furanosyl)acetone; With sodium methylate; In methanol; at 20 ℃; for 2h;

cyclohexylamine; In methanol; at 20 ℃; for 48h;

DOI:10.1016/j.carres.2009.08.028

Reference yield: 70.0%

1-C-(2,3-di-O-benzyl-6-C-nitro-6-deoxy-α-D-ribo-hex-5-eno-furanosyl)acetone (1168137-25-4) + benzylamine (100-46-9) → (1S,5R,6S,7R,8R,9S)-2-benzyl-6,7-di-O-benzyl-8-hydroxy-3-methyl-9-nitro-2-azabicyclo[3.3.1]nonan-3-ene + (1R,2S,3R,4R,5S,6R)-1-acetylmethyl-5-benzylamino-2,3-di-O-benzyl-4-hydroxy-6-nitrocyclohexane (1198581-82-6)

Guidance literature:

1-C-(2,3-di-O-benzyl-6-C-nitro-6-deoxy-α-D-ribo-hex-5-eno-furanosyl)acetone; With sodium methylate; In methanol; at 20 ℃; for 2h;

benzylamine; In methanol; at 20 ℃; for 48h;

DOI:10.1016/j.carres.2009.08.028

upstream raw materials:

C₂₃H₂₇NO₇

Downstream raw materials:

4-(1-C-acetylmethyl-2,3-di-O-benzyl-α-D-erythrofuranoside-4S)-2H-1,2,3-triazole

(3R,4S,5S,6S)-6-acetylmethyl-4,5-di-O-benzyl-3-hydroxypyrido[1,5-c]-1,2,3-triazole

(1R,2S,3R,4R)-1-acetylmethyl-2,3-di-O-benzyl-4-hydroxy-6-nitrocyclohex-5-ene

(1R,2S,3R,4R,5S,6S)-1-acetylmethyl-2,3-di-O-benzyl-4-hydroxy-5-methoxy-6-nitrocyclohexane