2H-Purin-2-one, 6-amino-9-beta-D-glucopyranosyl-1,9-dihydro-

Base Information

• Chemical Name: 2H-Purin-2-one, 6-amino-9-beta-D-glucopyranosyl-1,9-dihydro-
• CAS No.: 64283-15-4
• Molecular Formula: C₁₁H₁₅N₅O₆
• Molecular Weight: 313.27
• Mol file: 64283-15-4.mol

Synonyms:2H-Purin-2-one, 6-amino-9-beta-D-glucopyranosyl-1,9-dihydro-

Chemical Property of 2H-Purin-2-one, 6-amino-9-beta-D-glucopyranosyl-1,9-dihydro-

Chemical Property:

• Melting Point: 279-282 °C (decomp)(Solv: water (7732-18-5))
• PKA: 8.22±0.40(Predicted)
• Density: 2.25g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2H-Purin-2-one, 6-amino-9-beta-D-glucopyranosyl-1,9-dihydro-

There total 3 articles about 2H-Purin-2-one, 6-amino-9-beta-D-glucopyranosyl-1,9-dihydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1R)-1-(2,6-diamino-purin-9-yl)-1,5-anhydro-D-glucitol (64414-75-1) → 6-amino-9-β-D-glucopyranosyl-3,9-dihydro-purin-2-one (64283-15-4)

Guidance literature:

With water; acetic acid; sodium nitrite;

DOI:10.1021/ja01151a052

Reference yield:

(1R)-tetra-O-acetyl-1-(6-amino-2-methanesulfonyl-purin-9-yl)-1,5-anhydro-D-glucitol → 6-amino-9-β-D-glucopyranosyl-3,9-dihydro-purin-2-one (64283-15-4)

Guidance literature:

With sodium hydroxide;

Reference yield:

(1R)-tetra-O-acetyl-1-(6-amino-2-methylsulfanyl-purin-9-yl)-1,5-anhydro-D-glucitol → 6-amino-9-β-D-glucopyranosyl-3,9-dihydro-purin-2-one (64283-15-4)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂O₂; acetic acid

2: aq. NaOH solution

With sodium hydroxide; dihydrogen peroxide; acetic acid;

upstream raw materials:

(1R)-1-(2,6-diamino-purin-9-yl)-1,5-anhydro-D-glucitol