trans-2-<2-(2',5'-dimethoxy-phenyl)-cyclopropyl>-4-oxo-3-propoxy-4H-1-benzopyran-6-carboxylic acid

Base Information

Chemical Name:trans-2-<2-(2',5'-dimethoxy-phenyl)-cyclopropyl>-4-oxo-3-propoxy-4H-1-benzopyran-6-carboxylic acid
CAS No.:79124-90-6
Molecular Formula:C₂₄H₂₄O₇
Molecular Weight:424.45
Hs Code.:

Synonyms:trans-2-<2-(2',5'-dimethoxy-phenyl)-cyclopropyl>-4-oxo-3-propoxy-4H-1-benzopyran-6-carboxylic acid

Suppliers and Price of trans-2-<2-(2',5'-dimethoxy-phenyl)-cyclopropyl>-4-oxo-3-propoxy-4H-1-benzopyran-6-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of trans-2-<2-(2',5'-dimethoxy-phenyl)-cyclopropyl>-4-oxo-3-propoxy-4H-1-benzopyran-6-carboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of trans-2-<2-(2',5'-dimethoxy-phenyl)-cyclopropyl>-4-oxo-3-propoxy-4H-1-benzopyran-6-carboxylic acid

There total 8 articles about trans-2-<2-(2',5'-dimethoxy-phenyl)-cyclopropyl>-4-oxo-3-propoxy-4H-1-benzopyran-6-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 79570-94-8
trans-2-<2-(2',5'-dimethoxy-phenyl)-cyclopropyl>-4-oxo-3-propoxy-4H-1-benzopyran-6-carboxylic acid, methyl ester

: 79124-90-6
trans-2-<2-(2',5'-dimethoxy-phenyl)-cyclopropyl>-4-oxo-3-propoxy-4H-1-benzopyran-6-carboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol; for 0.166667h; Heating;

Reference yield:

: 57009-12-8
methyl 3-acetyl-4-hydroxybenzoate

: 79124-90-6
trans-2-<2-(2',5'-dimethoxy-phenyl)-cyclopropyl>-4-oxo-3-propoxy-4H-1-benzopyran-6-carboxylic acid

Guidance literature:: Multi-step reaction with 9 steps

1: 95 percent / pyridine / 20 h / Ambient temperature

2: bromine, CaCO₃ / CH₂Cl₂ / 16 h / Ambient temperature

3: dimethylformamide / 20 h / Ambient temperature

4: acetic anhydride, triethylamine / 20 h / Heating

5: 81 percent / 2.5 percent KOH / methanol / 2 h / Heating

6: 72 percent / K₂CO₃ / dimethylformamide / 20 h / 50 °C

7: 62 percent / sodium methylate / methanol / 20 h / Ambient temperature

8: 1.) 50 percent sodium hydride / 1.) dimethylformamide, r.t., 2 h; 2.) dimethylformamide, r.t., 6 h

9: 70 percent / 1 percent KOH / aq. ethanol / 0.17 h / Heating

With potassium hydroxide; bromine; sodium methylate; acetic anhydride; sodium hydride; potassium carbonate; triethylamine; calcium carbonate; In pyridine; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 78581-52-9
4-acetoxy-3-acetyl-benzoic acid, methyl ester

: 79124-90-6
trans-2-<2-(2',5'-dimethoxy-phenyl)-cyclopropyl>-4-oxo-3-propoxy-4H-1-benzopyran-6-carboxylic acid

Guidance literature:: Multi-step reaction with 8 steps

1: bromine, CaCO₃ / CH₂Cl₂ / 16 h / Ambient temperature

2: dimethylformamide / 20 h / Ambient temperature

3: acetic anhydride, triethylamine / 20 h / Heating

4: 81 percent / 2.5 percent KOH / methanol / 2 h / Heating

5: 72 percent / K₂CO₃ / dimethylformamide / 20 h / 50 °C

6: 62 percent / sodium methylate / methanol / 20 h / Ambient temperature

7: 1.) 50 percent sodium hydride / 1.) dimethylformamide, r.t., 2 h; 2.) dimethylformamide, r.t., 6 h

8: 70 percent / 1 percent KOH / aq. ethanol / 0.17 h / Heating

With potassium hydroxide; bromine; sodium methylate; acetic anhydride; sodium hydride; potassium carbonate; triethylamine; calcium carbonate; In methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;