Technology Process of C46H69N5O13
There total 8 articles about C46H69N5O13 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C16H16N2O4;
With
N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 0.25h;
Inert atmosphere;
3,9-Bis(tert-butoxycarbonylmethyl)-6-carboxymethyl-3,6,9-triazaundecanedioic acid-di-tert-butyl ester;
With
O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 24.4167h;
Inert atmosphere;
DOI:10.1021/ic402643a
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: phosphorus pentabromide / 3 h / 80 °C
2.1: 0.75 h / 0 °C
3.1: potassium phosphate; palladium diacetate; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane / 1,4-dioxane / 12 h / Reflux
4.1: trifluoroacetic acid / dichloromethane / 20 °C
5.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.25 h / 20 °C / Inert atmosphere
5.2: 24.42 h / 20 °C / Inert atmosphere
With
dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate; phosphorus pentabromide; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;
3.1: |Suzuki-Miyaura Coupling;
DOI:10.1021/ic402643a
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium phosphate; palladium diacetate; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane / 1,4-dioxane / 12 h / Reflux
2.1: trifluoroacetic acid / dichloromethane / 20 °C
3.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.25 h / 20 °C / Inert atmosphere
3.2: 24.42 h / 20 °C / Inert atmosphere
With
dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;
1.1: |Suzuki-Miyaura Coupling;
DOI:10.1021/ic402643a
