12-(4-ethylphenyl)-4b,6-dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinoline

Base Information

Chemical Name:12-(4-ethylphenyl)-4b,6-dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinoline
CAS No.:1443761-90-7
Molecular Formula:C₂₄H₂₁NO
Molecular Weight:339.437
Hs Code.:

Synonyms:12-(4-ethylphenyl)-4b,6-dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinoline

Suppliers and Price of 12-(4-ethylphenyl)-4b,6-dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 12-(4-ethylphenyl)-4b,6-dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinoline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 12-(4-ethylphenyl)-4b,6-dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinoline

There total 2 articles about 12-(4-ethylphenyl)-4b,6-dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 5344-90-1
2-Aminobenzyl alcohol

: 1383274-53-0
2-((4-ethylphenyl)ethynyl)benzaldehyde

: 1443761-90-7
12-(4-ethylphenyl)-4b,6-dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinoline

Guidance literature:: With silver nitrate; In water; at 80 ℃;
DOI:10.1021/jo4009639

Reference yield:

: 40307-11-7
1-ethyl-4-ethynylbenzene

: 1443761-90-7
12-(4-ethylphenyl)-4b,6-dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: bis-triphenylphosphine-palladium(II) chloride; triethylamine / acetonitrile / 70 °C

2: silver nitrate / water / 80 °C

With bis-triphenylphosphine-palladium(II) chloride; silver nitrate; triethylamine; In water; acetonitrile; 1: |Sonogashira Cross-Coupling;
DOI:10.1021/jo4009639