2-acetylamino-3-cyclohexyl-2,3-dideuteriopropanoic acid methyl ester

Base Information

• Chemical Name: 2-acetylamino-3-cyclohexyl-2,3-dideuteriopropanoic acid methyl ester
• CAS No.: 1018969-29-3
• Molecular Formula: C₁₂H₂₁NO₃
• Molecular Weight: 229.288
• Mol file: 1018969-29-3.mol

Synonyms:2-acetylamino-3-cyclohexyl-2,3-dideuteriopropanoic acid methyl ester

Chemical Property of 2-acetylamino-3-cyclohexyl-2,3-dideuteriopropanoic acid methyl ester

Chemical Property:

Purity/Quality:

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Technology Process of 2-acetylamino-3-cyclohexyl-2,3-dideuteriopropanoic acid methyl ester

There total 1 articles about 2-acetylamino-3-cyclohexyl-2,3-dideuteriopropanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(Z)-methyl 2-acetamido-3-cyclohexylacrylate → 2-acetylamino-3-cyclohexyl-2,3-dideuteriopropanoic acid methyl ester (1018969-29-3)

Guidance literature:

With samarium diiodide; water-d2; In tetrahydrofuran; at 20 ℃; for 0.5h;

DOI:10.1055/s-2008-1032063

Reference yield: 100.0%

2-acetylamino-3-cyclohexyl-2,3-dideuteriopropanoic acid methyl ester (1018969-29-3) → 2-amino-3-cyclohexyl-2,3-dideuteriopropanoic acid hydrochloride

Guidance literature:

With hydrogenchloride; for 12h; Heating;

DOI:10.1055/s-2008-1032063

Reference yield: 83.0%

2-acetylamino-3-cyclohexyl-2,3-dideuteriopropanoic acid methyl ester (1018969-29-3) → 2-acetylamino-3-cyclohexyl-2,3-dideuteriopropan-1-ol

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 12h;

DOI:10.1055/s-2008-1032063