CY 625

Base Information

• Chemical Name: CY 625
• CAS No.: 181116-85-8
• Molecular Formula: C₂₆H₄₂O₃
• Molecular Weight: 402.618
• Mol file: 181116-85-8.mol

Synonyms:CY 625

Chemical Property of CY 625

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of CY 625

There total 10 articles about CY 625 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(R)-7-{(S)-3-[2-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-1-methyl-cyclohexyl}-2,6-dimethyl-oct-7-en-2-ol (181116-89-2) → CY 625 (181116-85-8)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 48h;

DOI:10.1016/0960-894X(96)00301-0

Reference yield:

3-methylcyclohexen-2-one (1193-18-6) → CY 625 (181116-85-8)

Guidance literature:

Multi-step reaction with 9 steps

2: TBAF / tetrahydrofuran / 2 h / Ambient temperature

3: PPh₃, imidazole, I₂ / tetrahydrofuran / 1 h

4: NaBH₄ / CH₂Cl₂; methanol / 5 h / -78 - -30 °C

5: CuI, Zn / ethanol; H₂O / -10 °C

6: PDC / CH₂Cl₂ / 24 h

7: 85 percent / n-BuLi / tetrahydrofuran / 4 h / -78 - -20 °C

8: 98 percent / tetrahydrofuran / 48 h / Ambient temperature

9: 90 percent / TBAF / tetrahydrofuran / 48 h

With 1H-imidazole; sodium tetrahydroborate; copper(l) iodide; dipyridinium dichromate; n-butyllithium; tetrabutyl ammonium fluoride; iodine; triphenylphosphine; zinc; In tetrahydrofuran; methanol; ethanol; dichloromethane; water;

DOI:10.1016/0960-894X(96)00301-0

Reference yield:

(S)-3-((S)-3-Iodo-2-methyl-1-methylene-propyl)-3-methyl-cyclohexanol → CY 625 (181116-85-8)

Guidance literature:

Multi-step reaction with 5 steps

1: CuI, Zn / ethanol; H₂O / -10 °C

2: PDC / CH₂Cl₂ / 24 h

3: 85 percent / n-BuLi / tetrahydrofuran / 4 h / -78 - -20 °C

4: 98 percent / tetrahydrofuran / 48 h / Ambient temperature

5: 90 percent / TBAF / tetrahydrofuran / 48 h

With copper(l) iodide; dipyridinium dichromate; n-butyllithium; tetrabutyl ammonium fluoride; zinc; In tetrahydrofuran; ethanol; dichloromethane; water;

DOI:10.1016/0960-894X(96)00301-0

upstream raw materials:

(R)-7-{(S)-3-[2-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-1-methyl-cyclohexyl}-2,6-dimethyl-oct-7-en-2-ol

3-methylcyclohexen-2-one

(S)-3-((S)-3-Iodo-2-methyl-1-methylene-propyl)-3-methyl-cyclohexanone

(R)-5-Methyl-6-((S)-1-methyl-3-oxo-cyclohexyl)-hept-6-enoic acid methyl ester