C₄₆H₄₈N₄O₁₈

Base Information

• Chemical Name: C₄₆H₄₈N₄O₁₈
• CAS No.: 1365254-72-3
• Molecular Formula: C₄₆H₄₈N₄O₁₈
• Molecular Weight: 944.903
• Mol file: 1365254-72-3.mol

Synonyms:C₄₆H₄₈N₄O₁₈

Chemical Property of C₄₆H₄₈N₄O₁₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₆H₄₈N₄O₁₈

There total 4 articles about C₄₆H₄₈N₄O₁₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C46H44N4O14 (1365254-73-4) → C46H48N4O18 + C46H48N4O18 (1365254-72-3)

Guidance literature:

With osmium(VIII) oxide; 4-methylmorpholine N-oxide; hydroquinidein 1,4-phthalazinediyl diether; In tetrahydrofuran; water; tert-butyl alcohol; at 20 ℃; optical yield given as %de; Inert atmosphere;

DOI:10.1016/j.tet.2012.01.080

Reference yield:

C26H38N2O12 (1365254-70-1) → C46H48N4O18 (1365254-72-3)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogenchloride / water; ethyl acetate / 10 h / 20 °C / Inert atmosphere

2: 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / tetrahydrofuran / 10 h / 20 °C / Inert atmosphere

3: osmium(VIII) oxide; 4-methylmorpholine N-oxide; hydroquinidein 1,4-phthalazinediyl diether / tetrahydrofuran; water; tert-butyl alcohol / 20 °C / Inert atmosphere

With 4-methyl-morpholine; hydrogenchloride; osmium(VIII) oxide; benzotriazol-1-ol; 4-methylmorpholine N-oxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; hydroquinidein 1,4-phthalazinediyl diether; In tetrahydrofuran; water; ethyl acetate; tert-butyl alcohol; 3: Sharpless asymmetric dihydroxylation;

DOI:10.1016/j.tet.2012.01.080

Reference yield:

C16H22N2O8*2ClH → C46H48N4O18 (1365254-72-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / tetrahydrofuran / 10 h / 20 °C / Inert atmosphere

2: osmium(VIII) oxide; 4-methylmorpholine N-oxide; hydroquinidein 1,4-phthalazinediyl diether / tetrahydrofuran; water; tert-butyl alcohol / 20 °C / Inert atmosphere

With 4-methyl-morpholine; osmium(VIII) oxide; benzotriazol-1-ol; 4-methylmorpholine N-oxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; hydroquinidein 1,4-phthalazinediyl diether; In tetrahydrofuran; water; tert-butyl alcohol; 2: Sharpless asymmetric dihydroxylation;

DOI:10.1016/j.tet.2012.01.080

upstream raw materials:

C₄₆H₄₄N₄O₁₄

C₁₅H₂₃NO₆

C₂₆H₃₈N₂O₁₂