(E)-5-[1-(tert-butoxycarbonyl)piperidin-4-yloxy]-2-[2-(3-cyanophenyl)ethen-1-yl]-1-(hydroxyacetyl)indoline

Base Information

Chemical Name:(E)-5-[1-(tert-butoxycarbonyl)piperidin-4-yloxy]-2-[2-(3-cyanophenyl)ethen-1-yl]-1-(hydroxyacetyl)indoline
CAS No.:405887-35-6
Molecular Formula:C₂₉H₃₃N₃O₅
Molecular Weight:503.598
Hs Code.:

Synonyms:(E)-5-[1-(tert-butoxycarbonyl)piperidin-4-yloxy]-2-[2-(3-cyanophenyl)ethen-1-yl]-1-(hydroxyacetyl)indoline

Suppliers and Price of (E)-5-[1-(tert-butoxycarbonyl)piperidin-4-yloxy]-2-[2-(3-cyanophenyl)ethen-1-yl]-1-(hydroxyacetyl)indoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-5-[1-(tert-butoxycarbonyl)piperidin-4-yloxy]-2-[2-(3-cyanophenyl)ethen-1-yl]-1-(hydroxyacetyl)indoline

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Technology Process of (E)-5-[1-(tert-butoxycarbonyl)piperidin-4-yloxy]-2-[2-(3-cyanophenyl)ethen-1-yl]-1-(hydroxyacetyl)indoline

There total 1 articles about (E)-5-[1-(tert-butoxycarbonyl)piperidin-4-yloxy]-2-[2-(3-cyanophenyl)ethen-1-yl]-1-(hydroxyacetyl)indoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 405887-34-5
(E)-1-(acetoxyacetyl)-5-[1-(tert-butoxycarbonyl)piperidin-4-yloxy]-2-[2-(3-cyanophenyl)ethen-1-yl]indoline

: 405887-35-6
(E)-5-[1-(tert-butoxycarbonyl)piperidin-4-yloxy]-2-[2-(3-cyanophenyl)ethen-1-yl]-1-(hydroxyacetyl)indoline

Guidance literature:: With potassium carbonate; In methanol; at 20 ℃; for 1h;
DOI:10.1248/cpb.55.1494

Reference yield:

: 405887-35-6
(E)-5-[1-(tert-butoxycarbonyl)piperidin-4-yloxy]-2-[2-(3-cyanophenyl)ethen-1-yl]-1-(hydroxyacetyl)indoline

: 405886-64-8
C₂₄H₂₈N₄O₃

Guidance literature:: (E)-5-[1-(tert-butoxycarbonyl)piperidin-4-yloxy]-2-[2-(3-cyanophenyl)ethen-1-yl]-1-(hydroxyacetyl)indoline; With hydrogenchloride; ethanol; In dichloromethane;

With ammonium hydroxide; ammonium chloride; In ethanol; Further stages.;
DOI:10.1248/cpb.55.1494