(S)-2-(tert-butyldiphenylsilyloxymethyl)-4,4-diethoxybutan-1-ol

Base Information

• Chemical Name: (S)-2-(tert-butyldiphenylsilyloxymethyl)-4,4-diethoxybutan-1-ol
• CAS No.: 908338-29-4
• Molecular Formula: C₂₅H₃₈O₄Si
• Molecular Weight: 430.66
• Mol file: 908338-29-4.mol

Synonyms:(S)-2-(tert-butyldiphenylsilyloxymethyl)-4,4-diethoxybutan-1-ol

Chemical Property of (S)-2-(tert-butyldiphenylsilyloxymethyl)-4,4-diethoxybutan-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-(tert-butyldiphenylsilyloxymethyl)-4,4-diethoxybutan-1-ol

There total 3 articles about (S)-2-(tert-butyldiphenylsilyloxymethyl)-4,4-diethoxybutan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(S)-2-(tert-butyldiphenylsilyloxymethyl)-4,4-diethoxybutyl acetate (908338-28-3) → (S)-2-(tert-butyldiphenylsilyloxymethyl)-4,4-diethoxybutan-1-ol (908338-29-4)

Guidance literature:

With potassium carbonate; In ethanol; at 20 ℃;

DOI:10.1016/j.bmc.2006.05.033

Reference yield:

(R)-2-(2,2-diethoxyethyl)-1,3-propanediol monoacetate (144461-19-8,134665-24-0) → (S)-2-(tert-butyldiphenylsilyloxymethyl)-4,4-diethoxybutan-1-ol (908338-29-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / imidazole / dimethylformamide / 0 °C

2: 98 percent / potassium carbonate / ethanol / 20 °C

With 1H-imidazole; potassium carbonate; In ethanol; N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2006.05.033

Reference yield:

tert-butylchlorodiphenylsilane (58479-61-1) → (S)-2-(tert-butyldiphenylsilyloxymethyl)-4,4-diethoxybutan-1-ol (908338-29-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / imidazole / dimethylformamide / 0 °C

2: 98 percent / potassium carbonate / ethanol / 20 °C

With 1H-imidazole; potassium carbonate; In ethanol; N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2006.05.033

upstream raw materials:

(S)-2-(tert-butyldiphenylsilyloxymethyl)-4,4-diethoxybutyl acetate

(R)-2-(2,2-diethoxyethyl)-1,3-propanediol monoacetate

tert-butylchlorodiphenylsilane