(S)-2,2,2-trifluoro-N-(1-(4-(N'-hydroxycarbamimidoyl)phenyl)ethyl)ethanamide

Base Information

Chemical Name:(S)-2,2,2-trifluoro-N-(1-(4-(N'-hydroxycarbamimidoyl)phenyl)ethyl)ethanamide
CAS No.:1218818-56-4
Molecular Formula:C₁₁H₁₂F₃N₃O₂
Molecular Weight:275.23
Hs Code.:

Synonyms:(S)-2,2,2-trifluoro-N-(1-(4-(N'-hydroxycarbamimidoyl)phenyl)ethyl)ethanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-2,2,2-trifluoro-N-(1-(4-(N'-hydroxycarbamimidoyl)phenyl)ethyl)ethanamide

Chemical Property:

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Technology Process of (S)-2,2,2-trifluoro-N-(1-(4-(N'-hydroxycarbamimidoyl)phenyl)ethyl)ethanamide

There total 1 articles about (S)-2,2,2-trifluoro-N-(1-(4-(N'-hydroxycarbamimidoyl)phenyl)ethyl)ethanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1235874-31-3
N-[(S)-1-(4-cyano-phenyl)-ethyl]-2,2,2-trifluoro-acetamide

: 1218818-56-4
(S)-2,2,2-trifluoro-N-(1-(4-(N'-hydroxycarbamimidoyl)phenyl)ethyl)ethanamide

Guidance literature:: With hydroxylamine hydrochloride; sodium hydrogencarbonate; In methanol; Reflux;
DOI:10.1016/j.bmcl.2010.06.019

Reference yield: 36.0%

: 104-97-2
cyclopentanepropanoyl chloride

: 1218818-56-4
(S)-2,2,2-trifluoro-N-(1-(4-(N'-hydroxycarbamimidoyl)phenyl)ethyl)ethanamide

: 1218817-94-7
(S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethanamine

Guidance literature:: cyclopentanepropanoyl chloride; (S)-2,2,2-trifluoro-N-(1-(4-(N'-hydroxycarbamimidoyl)phenyl)ethyl)ethanamide; With pyridine; for 18h; Reflux;

With lithium hydroxide monohydrate; In tetrahydrofuran; water; at 20 ℃; for 18h;