tert-butyl (4S,5R,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-chlorotetrahydro-2H-pyran-2-ylcarbamate

Base Information

• Chemical Name: tert-butyl (4S,5R,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-chlorotetrahydro-2H-pyran-2-ylcarbamate
• CAS No.: 1129725-34-3
• Molecular Formula: C₃₂H₃₈ClNO₆
• Molecular Weight: 568.11
• Mol file: 1129725-34-3.mol

Synonyms:tert-butyl (4S,5R,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-chlorotetrahydro-2H-pyran-2-ylcarbamate

Chemical Property of tert-butyl (4S,5R,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-chlorotetrahydro-2H-pyran-2-ylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl (4S,5R,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-chlorotetrahydro-2H-pyran-2-ylcarbamate

There total 1 articles about tert-butyl (4S,5R,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-chlorotetrahydro-2H-pyran-2-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

di-tert-butyl dicarbonate (24424-99-5) + C27H30ClNO4 (1129725-26-3) → tert-butyl (4S,5R,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-chlorotetrahydro-2H-pyran-2-ylcarbamate (1129725-34-3)

Guidance literature:

With sodium hydrogencarbonate; In water; ethyl acetate; at 20 ℃;

DOI:10.1002/ejoc.200800796

Reference yield: 80.0%

tert-butyl (4S,5R,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-chlorotetrahydro-2H-pyran-2-ylcarbamate (1129725-34-3) → tert-butyl (4R,5S,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-ylcarbamate (1129725-41-2)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tributyltin chloride; sodium cyanoborohydride; In tert-butyl alcohol; for 2h; Reflux;

DOI:10.1002/ejoc.200800796

upstream raw materials:

di-tert-butyl dicarbonate

C₂₇H₃₀ClNO₄

Downstream raw materials:

tert-butyl (4R,5S,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-ylcarbamate