3-[(2-Amino-6-chloropyrimidin-4-yl)amino]-5-(hydroxymethyl)cyclopentane-1,2-diol

Base Information

Chemical Name:3-[(2-Amino-6-chloropyrimidin-4-yl)amino]-5-(hydroxymethyl)cyclopentane-1,2-diol
CAS No.:50619-38-0
Molecular Formula:C₁₀H₁₅ClN₄O₃
Molecular Weight:274.707
Hs Code.:
NSC Number:128723
DSSTox Substance ID:DTXSID20299196

Synonyms:50619-38-0;3-[(2-amino-6-chloropyrimidin-4-yl)amino]-5-(hydroxymethyl)cyclopentane-1,2-diol;3-((2-Amino-6-chloropyrimidin-4-yl)amino)-5-(hydroxymethyl)cyclopentane-1,2-diol;NSC128723;DTXSID20299196;NSC-128723

Suppliers and Price of 3-[(2-Amino-6-chloropyrimidin-4-yl)amino]-5-(hydroxymethyl)cyclopentane-1,2-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 3-[(2-Amino-6-chloropyrimidin-4-yl)amino]-5-(hydroxymethyl)cyclopentane-1,2-diol

Chemical Property:

Vapor Pressure:1.61E-15mmHg at 25°C
Boiling Point:605.7°C at 760 mmHg
Flash Point:320.1°C
Density:1.646g/cm³
XLogP3:0.2
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:274.0832680
Heavy Atom Count:18
Complexity:286

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(C(C1NC2=CC(=NC(=N2)N)Cl)O)O)CO

Technology Process of 3-[(2-Amino-6-chloropyrimidin-4-yl)amino]-5-(hydroxymethyl)cyclopentane-1,2-diol

There total 2 articles about 3-[(2-Amino-6-chloropyrimidin-4-yl)amino]-5-(hydroxymethyl)cyclopentane-1,2-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 56-05-3
2-Amino-4,6-dichloropyrimidine

: 79200-57-0
(1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxylmethyl)-1-aminocyclopentan hydrochloride

: 50619-38-0,75829-34-4,108742-05-8,125073-22-5
3-(2-amino-6-chloro-pyrimidin-4-ylamino)-5-hydroxymethyl-cyclopentane-1,2-diol

Guidance literature:: With triethylamine; In ethanol; for 16h; Reflux;
DOI:10.1016/j.bmcl.2011.11.091

Reference yield:

: 50619-38-0,75829-34-4,108742-05-8,125073-22-5
3-(2-amino-6-chloro-pyrimidin-4-ylamino)-5-hydroxymethyl-cyclopentane-1,2-diol

Guidance literature:: 2-Amino-4,6-dichlorpyrimidin (I), trans-3-Amino-trans-5-(hydroxymethyl)-cis-1,2-cyclopentandiol / Ethanol, Triethylamin;
DOI:10.1002/jps.2600620907