(4-Ethynylphenyl)-diphenylmethanol

Base Information

Chemical Name:(4-Ethynylphenyl)-diphenylmethanol
CAS No.:136443-08-8
Molecular Formula:C₂₁H₁₆O
Molecular Weight:284.357
Hs Code.:
DSSTox Substance ID:DTXSID801285221
Nikkaji Number:J497.671A

Synonyms:136443-08-8;(4-ethynylphenyl)-diphenylmethanol;4-ethynyl-alpha,alpha-diphenyl-Benzenemethanol;SCHEMBL8048733;(4-ethynylphenyl)diphenylmethanol;TTYBGMUDYSDEID-UHFFFAOYSA-N;DTXSID801285221

Suppliers and Price of (4-Ethynylphenyl)-diphenylmethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4-Ethynylphenyl)-diphenylmethanol

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:284.120115130
Heavy Atom Count:22
Complexity:365

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C#CC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)O

Technology Process of (4-Ethynylphenyl)-diphenylmethanol

There total 5 articles about (4-Ethynylphenyl)-diphenylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 143870-52-4
4-<(3-hydroxy-3-methyl-1-butynyl)phenyl>diphenylmethanol

: 136443-08-8
(4-ethynylphenyl)diphenylmethanol

Guidance literature:: With sodium hydroxide; In toluene; for 3h; Heating;
DOI:10.1055/s-1992-26210

Reference yield:

: 108-86-1,52753-63-6
bromobenzene

: 136443-08-8
(4-ethynylphenyl)diphenylmethanol

Guidance literature:: Multi-step reaction with 3 steps

1: 1) Mg / 1) Et₂O, reflux, 30 min, 2) benzene, Et₂O, r.t., overnight

2: 90 percent / i-PrOH, water, TsOH / 2 h / Heating

3: 60 percent / NaOH / toluene / 3 h / Heating

With sodium hydroxide; water; toluene-4-sulfonic acid; magnesium; isopropyl alcohol; In toluene;
DOI:10.1055/s-1992-26210

Reference yield:

: 143870-50-2
4-(3-methyl-3-tetrahydropyranyloxy-1-butynyl)benzophenone

: 136443-08-8
(4-ethynylphenyl)diphenylmethanol

Guidance literature:: Multi-step reaction with 3 steps

1: 1) Mg / 1) Et₂O, reflux, 30 min, 2) benzene, Et₂O, r.t., overnight

2: 90 percent / i-PrOH, water, TsOH / 2 h / Heating

3: 60 percent / NaOH / toluene / 3 h / Heating

With sodium hydroxide; water; toluene-4-sulfonic acid; magnesium; isopropyl alcohol; In toluene;
DOI:10.1055/s-1992-26210