Technology Process of C13H12ClN3O*ClH
There total 5 articles about C13H12ClN3O*ClH which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C13H11ClN2O2;
With
pyridine; di-tert-butyl dicarbonate; ammonium bicarbonate;
In
1,4-dioxane;
at 0 - 20 ℃;
With
dimethylsulfide borane complex;
In
tetrahydrofuran; methanol;
at 0 - 70 ℃;
for 3h;
With
hydrogenchloride;
In
1,4-dioxane; diethyl ether;
at 0 ℃;
pH=4;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: acetic acid / 2-methoxy-ethanol / 3 h / 105 °C
2.1: lithium hydroxide / tetrahydrofuran; methanol
3.1: di-tert-butyl dicarbonate; pyridine; ammonium bicarbonate / 1,4-dioxane / 0 - 20 °C
3.2: 3 h / 0 - 70 °C
3.3: 0 °C / pH 4
With
pyridine; di-tert-butyl dicarbonate; ammonium bicarbonate; acetic acid; lithium hydroxide;
In
tetrahydrofuran; 1,4-dioxane; methanol; 2-methoxy-ethanol;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: lithium hydroxide / tetrahydrofuran; methanol
2.1: di-tert-butyl dicarbonate; pyridine; ammonium bicarbonate / 1,4-dioxane / 0 - 20 °C
2.2: 3 h / 0 - 70 °C
2.3: 0 °C / pH 4
With
pyridine; di-tert-butyl dicarbonate; ammonium bicarbonate; lithium hydroxide;
In
tetrahydrofuran; 1,4-dioxane; methanol;