N-(2-(4-chlorophenyl)-5-hydroxy-5-methylhex-3-yn-2-yl)-P,P-diphenylphosphinothioic amide

Base Information

Chemical Name:N-(2-(4-chlorophenyl)-5-hydroxy-5-methylhex-3-yn-2-yl)-P,P-diphenylphosphinothioic amide
CAS No.:1419873-41-8
Molecular Formula:C₂₅H₂₅ClNOPS
Molecular Weight:453.972
Hs Code.:

Synonyms:N-(2-(4-chlorophenyl)-5-hydroxy-5-methylhex-3-yn-2-yl)-P,P-diphenylphosphinothioic amide

Suppliers and Price of N-(2-(4-chlorophenyl)-5-hydroxy-5-methylhex-3-yn-2-yl)-P,P-diphenylphosphinothioic amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(2-(4-chlorophenyl)-5-hydroxy-5-methylhex-3-yn-2-yl)-P,P-diphenylphosphinothioic amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(2-(4-chlorophenyl)-5-hydroxy-5-methylhex-3-yn-2-yl)-P,P-diphenylphosphinothioic amide

There total 1 articles about N-(2-(4-chlorophenyl)-5-hydroxy-5-methylhex-3-yn-2-yl)-P,P-diphenylphosphinothioic amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 1138700-38-5
N-1-(4-chlorophenyl)ethylidene-diphenylthiophosphinamide

: 115-19-5
2-methyl-but-3-yn-2-ol

: 1419873-41-8
N-(2-(4-chlorophenyl)-5-hydroxy-5-methylhex-3-yn-2-yl)-P,P-diphenylphosphinothioic amide

Guidance literature:: 2-methyl-but-3-yn-2-ol; With mesitylcopper(I); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In toluene; at 20 ℃; for 0.166667h; Inert atmosphere;

N-1-(4-chlorophenyl)ethylidene-diphenylthiophosphinamide; In toluene; at 70 ℃; for 48h; Inert atmosphere;
DOI:10.1021/ol3035609

Reference yield: 86.0%

: 1419873-41-8
N-(2-(4-chlorophenyl)-5-hydroxy-5-methylhex-3-yn-2-yl)-P,P-diphenylphosphinothioic amide

: 1419873-67-8
N-(2-(4-chlorophenyl)but-3-yn-2-yl)-P,P-diphenylphosphinothioic amide

Guidance literature:: With 18-crown-6 ether; potassium carbonate; In toluene; for 16h; Molecular sieve; Reflux; Inert atmosphere;
DOI:10.1021/ol3035609

Reference yield:

: 1419873-41-8
N-(2-(4-chlorophenyl)-5-hydroxy-5-methylhex-3-yn-2-yl)-P,P-diphenylphosphinothioic amide

: 2-(4-chlorophenyl)butan-2-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 18-crown-6 ether; potassium carbonate / toluene / 16 h / Molecular sieve; Reflux; Inert atmosphere

2: potassium diazodicarboxylate; acetic acid / methanol / 24 h / 20 °C

3: hydrogen / ethanol / 15 h / 70 °C

With 18-crown-6 ether; hydrogen; potassium diazodicarboxylate; potassium carbonate; acetic acid; In methanol; ethanol; toluene;
DOI:10.1021/ol3035609