bis{3-[2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylbenzyl]-2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylphenyl}methane

Base Information

• Chemical Name: bis{3-[2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylbenzyl]-2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylphenyl}methane
• CAS No.: 250352-83-1
• Molecular Formula: C₅₁H₆₈O₁₂P₄
• Molecular Weight: 996.989
• Mol file: 250352-83-1.mol

Synonyms:bis{3-[2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylbenzyl]-2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylphenyl}methane

Chemical Property of bis{3-[2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylbenzyl]-2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylphenyl}methane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis{3-[2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylbenzyl]-2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylphenyl}methane

There total 4 articles about bis{3-[2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylbenzyl]-2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylphenyl}methane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-diethylamino-5,5-dimethyl-1,3,2-dioxaphosphorinane (21458-75-3) + 6,6′-methylenebis(2-(2-hydroxy-5-methylbenzyl)-4-methylphenol) (20837-68-7) → bis{3-[2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylbenzyl]-2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylphenyl}methane (250352-83-1)

Guidance literature:

In acetonitrile; at 80 - 100 ℃; for 1.5h; under 1 - 760 Torr;

Reference yield:

p-cresol (106-44-5) → bis{3-[2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylbenzyl]-2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylphenyl}methane (250352-83-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 42 percent / p-toluenesulfonic acid / benzene / 0.5 h / 100 °C

2: 85 percent / acetonitrile / 1.5 h / 80 - 100 °C / 1 - 760 Torr

With toluene-4-sulfonic acid; In acetonitrile; benzene; 1: Alkylation / 2: Esterification;

Reference yield:

2,2'-methylenebis(4-methylphenol) (3236-63-3) → bis{3-[2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylbenzyl]-2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)-5-methylphenyl}methane (250352-83-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 46 percent / sodium hydroxide / H₂O; methanol / 24 h / 50 °C

2: 42 percent / p-toluenesulfonic acid / benzene / 0.5 h / 100 °C

3: 85 percent / acetonitrile / 1.5 h / 80 - 100 °C / 1 - 760 Torr

With sodium hydroxide; toluene-4-sulfonic acid; In methanol; water; acetonitrile; benzene; 1: Alkylation / 2: Alkylation / 3: Esterification;

upstream raw materials:

2-diethylamino-5,5-dimethyl-1,3,2-dioxaphosphorinane

6,6′-methylenebis(2-(2-hydroxy-5-methylbenzyl)-4-methylphenol)

p-cresol

2,2'-methylenebis(4-methylphenol)