3-Pentanone, (1-ethylpropylidene)hydrazone

Base Information

• Chemical Name: 3-Pentanone, (1-ethylpropylidene)hydrazone
• CAS No.: 1530-17-2
• Molecular Formula: C10H20 N2
• Molecular Weight: 168.282
• DSSTox Substance ID: DTXSID60165189
• Nikkaji Number: J192.672A
• Mol file: 1530-17-2.mol

Synonyms:Diethyl ketazine;3-Pentanone, azine;BRN 1759982;3-Pentanone, (1-ethylpropylidene)hydrazone;1530-17-2;4-01-00-03283 (Beilstein Handbook Reference);pentan-3-one azine;3,3'-Azinodipentane;DTXSID60165189;LS-101969

Chemical Property of 3-Pentanone, (1-ethylpropylidene)hydrazone

Chemical Property:

• Vapor Pressure: 0.184mmHg at 25°C
• Boiling Point: 218.6°C at 760 mmHg
• Flash Point: 77.5°C
• Density: 0.84g/cm³
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 168.162648646
• Heavy Atom Count: 12
• Complexity: 137

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(=NN=C(CC)CC)CC

Technology Process of 3-Pentanone, (1-ethylpropylidene)hydrazone

There total 4 articles about 3-Pentanone, (1-ethylpropylidene)hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2-pentanol (584-02-1) → diethyl ketone azine (1530-17-2)

Guidance literature:

With [carbonylchlorohydrido{bis[2-(diphenylphosphinomethyl)ethyl]amino}ethylamino] ruthenium(II); potassium tert-butylate; hydrazine hydrate; In toluene; at 125 ℃; for 12h; Schlenk technique; Molecular sieve; Inert atmosphere; Green chemistry;

DOI:10.1039/c9cc01383k

Reference yield:

pentan-3-one (96-22-0) → diethyl ketone azine (1530-17-2)

Guidance literature:

With hydrazine hydrate;

Reference yield:

ethylmagnesium bromide (925-90-6) + propiononitrile (107-12-0) → diethyl ketone azine (1530-17-2)

Guidance literature:

Multistep reaction; (i), (ii) CuCl, THF, (iii) O₂;

upstream raw materials:

pentan-3-one

ethylmagnesium bromide

propiononitrile

2-pentanol

Downstream raw materials:

3-aminopentane

1-(3-chloro-4-methylphenyl)-3-{2-[(1-ethylpropylidene)hydrazono]-1-methylbutyl}pyrrolidine-2,5-dione

3-{2-[(1-ethylpropylidene)hydrazono]-1-methylbutyl}-1-(4-iodophenyl)pyrrolidine-2,5-dione

N-(1-ethylpropyl)-N'-phenylurea

Refernces

• 1、 Kishore, Jugal,Thiyagarajan, Subramanian,Gunanathan, Chidambaram. "Ruthenium(ii)-catalysed direct synthesis of ketazines using secondary alcohols". supporting information. p. 4542 - 4545. Retrieved 2019/04/26.