3-Acetylaminocarbazole

Base Information

• Chemical Name: 3-Acetylaminocarbazole
• CAS No.: 57102-95-1
• Molecular Formula: C₁₄H₁₂N₂O
• Molecular Weight: 224.262
• DSSTox Substance ID: DTXSID30205723
• Nikkaji Number: J524.454D
• Wikidata: Q83079364
• ChEMBL ID: CHEMBL60001
• Mol file: 57102-95-1.mol

Synonyms:3-Acetylaminocarbazole;N-(9H-Carbazol-3-yl)acetamide;57102-95-1;CHEMBL60001;CCRIS 6506;3-Acetamidocarbazole;N-3-Carbazolylacetamide;Acetamide, N-3-carbazolyl-;Oprea1_221789;MLS000089840;N-9H-carbazol-3-ylacetamide;SCHEMBL7722965;NIOSH/AB5004920;DTXSID30205723;JWFQIJOWFMAEMA-UHFFFAOYSA-N;HMS2506C19;N-(9H-Carbazol-3-yl)acetamide #;BDBM50471124;AKOS002242696;SMR000024458;AB50049200;EU-0042285;AP-124/40683332;SR-01000082074;SR-01000082074-1

Chemical Property of 3-Acetylaminocarbazole

Chemical Property:

• Vapor Pressure: 1.63E-11mmHg at 25°C
• Boiling Point: 534.8°Cat760mmHg
• Flash Point: 277.2°C
• PSA: 48.38000
• Density: 1.326g/cm³
• LogP: 3.92900
• XLogP3: 3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 224.094963011
• Heavy Atom Count: 17
• Complexity: 305

Purity/Quality:

99%min ^*data from raw suppliers

3-ACETYLAMINOCARBAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=CC2=C(C=C1)NC3=CC=CC=C32

Technology Process of 3-Acetylaminocarbazole

There total 5 articles about 3-Acetylaminocarbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

acetic anhydride (108-24-7) + 3-nitro-6-methoxy-9H-carbazole (155136-79-1) → 3-acetamidocarbazole (57102-95-1) + 3-acetamido-6-methoxy-9H-carbazole

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; at 20 - 50 ℃; for 18h; under 3040 Torr;

DOI:10.1021/jm960651z

Reference yield:

N-(6,2'-diamino-biphenyl-3-yl)-acetamide (856047-96-6) → 3-acetamidocarbazole (57102-95-1)

Guidance literature:

With hydrogenchloride; at 200 ℃; Behandeln des Reaktionsprodukts mit Acetanhydrid;

DOI:10.1039/jr9450000824

Reference yield:

3-Nitro-carbazol (3077-85-8) → 3-acetamidocarbazole (57102-95-1)

Guidance literature:

Multi-step reaction with 2 steps

1: tin; hydrochloric acid

With hydrogenchloride; tin;

upstream raw materials:

3-amino-9H-carbazole

acetic anhydride

N-(6,2'-diamino-biphenyl-3-yl)-acetamide

3-nitro-6-methoxy-9H-carbazole

Refernces