Technology Process of 3-azidopropyl ((methyl 2,3-di-O-benzyl-4-O-(methyl 2,3-di-O-benzyl-β-D-mannopyranosyl)uronate)-β-D-mannopyranoside)uronate
There total 11 articles about 3-azidopropyl ((methyl 2,3-di-O-benzyl-4-O-(methyl 2,3-di-O-benzyl-β-D-mannopyranosyl)uronate)-β-D-mannopyranoside)uronate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 86 percent / pyridine / dioxane / 20 °C
2: 78 percent / N-iodosuccinimide; trimethylsilyl trifluoromethanesulfonate / CH2Cl2 / -40 - 20 °C
3: 95 percent / N2H4*H2O / pyridine; acetic acid / 0.5 h / 20 °C
With
pyridine; N-iodo-succinimide; trimethylsilyl trifluoromethanesulfonate; hydrazine hydrate;
In
1,4-dioxane; pyridine; dichloromethane; acetic acid;
DOI:10.1021/ja064787q
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 95 percent / K2CO3 / dimethylformamide / 10 h / 20 °C
2: 86 percent / pyridine / dioxane / 20 °C
3: 78 percent / N-iodosuccinimide; trimethylsilyl trifluoromethanesulfonate / CH2Cl2 / -40 - 20 °C
4: 95 percent / N2H4*H2O / pyridine; acetic acid / 0.5 h / 20 °C
With
pyridine; N-iodo-succinimide; trimethylsilyl trifluoromethanesulfonate; potassium carbonate; hydrazine hydrate;
In
1,4-dioxane; pyridine; dichloromethane; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/ja064787q
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: Ph2SO; tri-tert-butylpyrimidine; triflic acid anhydride / CH2Cl2 / 0.25 h / -40 °C
1.2: CH2Cl2 / -80 - 20 °C
1.3: 80 percent / pyridine / CH2Cl2 / 10 h / 20 °C
2.1: 60 percent / NaOMe / methanol / 6 h / 20 °C
3.1: 78 percent / N-iodosuccinimide; trimethylsilyl trifluoromethanesulfonate / CH2Cl2 / -40 - 20 °C
4.1: 95 percent / N2H4*H2O / pyridine; acetic acid / 0.5 h / 20 °C
With
N-iodo-succinimide; trifluoromethylsulfonic anhydride; trimethylsilyl trifluoromethanesulfonate; 1,1'-sulfinylbisbenzene; 2,4,5-tri-tert-butylpyrimidine; sodium methylate; hydrazine hydrate;
In
pyridine; methanol; dichloromethane; acetic acid;
DOI:10.1021/ja064787q
