2-(1H-Imidazol-2-YL)ethanamine dihydrochloride

Base Information

• Chemical Name: 2-(1H-Imidazol-2-YL)ethanamine dihydrochloride
• CAS No.: 17286-47-4
• Molecular Formula: C₅H₉N₃*2ClH
• Molecular Weight: 184.068
• Hs Code.: 2933998090
• European Community (EC) Number: 845-763-8,942-256-4
• Mol file: 17286-47-4.mol

Synonyms:17286-47-4;2-(1H-IMIDAZOL-2-YL)ETHANAMINE DIHYDROCHLORIDE;[2-(1H-IMIDAZOL-2-YL)ETHYL]AMINE DIHYDROCHLORIDE;2-(2-Imidazolyl)ethanamine Dihydrochloride;2-(1H-imidazol-2-yl)ethanamine;dihydrochloride;MFCD08668396;1H-Imidazole-2-ethanamine, dihydrochloride;SCHEMBL1430250;1H-Imidazole-2-ethanamine 2HCl;AKOS015894594;CS-W007216;DS-9733;1H-Imidazole-2-ethanamine (2HCl salt);SY059809;2-(1H-IMIDAZOL-2-YL)ETHANAMINE 2HCL;EN300-73975;F18351;A881835;2-(1H-imidazol-2-yl)ethan-1-amine dihydrochloride

Chemical Property of 2-(1H-Imidazol-2-YL)ethanamine dihydrochloride

Chemical Property:

• Storage Temp.: Inert atmosphere,Room Temperature
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 183.0330028
• Heavy Atom Count: 10
• Complexity: 64.7

Purity/Quality:

99.3% ^*data from raw suppliers

2-(1H-Imidazol-2-yl)ethanaminedihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN=C(N1)CCN.Cl.Cl

Technology Process of 2-(1H-Imidazol-2-YL)ethanamine dihydrochloride

There total 1 articles about 2-(1H-Imidazol-2-YL)ethanamine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

N-[2-(1H-imidazol-2-yl)-ethyl]-phthalimide (88883-77-6) → [2-(1H-imidazol-2-yl)ethyl]amine dihydrochloride (17286-47-4)

Guidance literature:

With hydrogenchloride; for 6h; Heating;

DOI:10.1002/ardp.19843170104

Reference yield: 91.0%

2-chloro-3-(4-fluorophenyl)quinoxaline-6-carbonyl chloride + [2-(1H-imidazol-2-yl)ethyl]amine dihydrochloride (17286-47-4) → 2-chloro-3-(4-fluorophenyl)-N-[2-(1H-imidazol-2-yl)ethyl]quinoxaline-6-carboxamide

Guidance literature:

With triethylamine; In N,N-dimethyl acetamide; at 20 ℃;

Reference yield:

C23H27IN2O5 + [2-(1H-imidazol-2-yl)ethyl]amine dihydrochloride (17286-47-4) → 3-(2-(2-((2-(1H-imidazol-2-yl)ethyl)amino)-2-oxoethoxy)phenyl)-N-(2-(2-(3-iodophenyl)-N-methylacetamido)ethyl)-N-methylpropanamide (1415657-86-1)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1021/jo302089f

upstream raw materials:

N-[2-(1H-imidazol-2-yl)-ethyl]-phthalimide

Downstream raw materials:

3-(2-(2-((2-(1H-imidazol-2-yl)ethyl)amino)-2-oxoethoxy)phenyl)-N-(2-(2-(3-iodophenyl)-N-methylacetamido)ethyl)-N-methylpropanamide

Refernces