(2S,3S)-2-benzyl-3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-4-nitrobutyraldehyde

Base Information

Chemical Name:(2S,3S)-2-benzyl-3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-4-nitrobutyraldehyde
CAS No.:1238305-35-5
Molecular Formula:C₁₉H₁₆N₂O₅
Molecular Weight:352.346
Hs Code.:

Synonyms:(2S,3S)-2-benzyl-3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-4-nitrobutyraldehyde

Suppliers and Price of (2S,3S)-2-benzyl-3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-4-nitrobutyraldehyde

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2S,3S)-2-benzyl-3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-4-nitrobutyraldehyde

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (2S,3S)-2-benzyl-3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-4-nitrobutyraldehyde

There total 2 articles about (2S,3S)-2-benzyl-3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-4-nitrobutyraldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 104-53-0
3-phenyl-propionaldehyde

: 1238305-33-3
(E)-2-(2-nitrovinyl)isoindoline-1,3-dione

: 1238305-35-5
(2S,3S)-2-benzyl-3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-4-nitrobutyraldehyde

: 2-benzyl-3-(1,3-dioxoisoindolin-2-yl)-4-nitrobutanal

Guidance literature:: With (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; acetic acid; In chloroform; water; at 0 - 22 ℃; for 18.5h; stereoselective reaction;
DOI:10.1002/ejoc.202000235

Reference yield:

: 104-53-0
3-phenyl-propionaldehyde

: 1238305-33-3
(E)-2-(2-nitrovinyl)isoindoline-1,3-dione

: 1238305-35-5
(2S,3S)-2-benzyl-3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-4-nitrobutyraldehyde

: 2-benzyl-3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-4-nitrobutyraldehyde

Guidance literature:: With acetic acid; In acetonitrile; at 0 ℃; for 7h; optical yield given as %ee; enantioselective reaction;
DOI:10.1002/anie.201001644