C₁₈H₂₁F₅N₂O₃

Base Information

Chemical Name:C₁₈H₂₁F₅N₂O₃
CAS No.:953083-87-9
Molecular Formula:C₁₈H₂₁F₅N₂O₃
Molecular Weight:408.368
Hs Code.:

C<sub>18</sub>H<sub>21</sub>F<sub>5</sub>N<sub>2</sub>O<sub>3</sub>

Synonyms:C₁₈H₂₁F₅N₂O₃

Suppliers and Price of C₁₈H₂₁F₅N₂O₃

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₈H₂₁F₅N₂O₃

Chemical Property:

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Technology Process of C₁₈H₂₁F₅N₂O₃

There total 6 articles about C₁₈H₂₁F₅N₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 953077-40-2
N-{(3Z)-4-(2,3-difluorophenyl)-1,1-dipropionyl-5-[(2,2,2-trifluoroethyl)amino]pent-3-en-1-yl}acetamide

: 953083-87-9
C₁₈H₂₁F₅N₂O₃

Guidance literature:: With water; lithium chloride; In ISOPROPYLAMIDE; at 113 - 115 ℃; for 12 - 14h;

Reference yield:

: 953077-38-8
2-(2,3-difluorophenyl)-2-vinyloxirane

: 953083-87-9
C₁₈H₂₁F₅N₂O₃

Guidance literature:: Multi-step reaction with 4 steps

1: sodium ethanolate / palladium diacetate; 1,2-bis-(diphenylphosphino)ethane / toluene / 6.25 - 10.25 h / 20 - 25 °C

2: triethylamine / toluene / 0.5 h / 3 °C

3: lithium bromide / ISOPROPYLAMIDE / 13 h / 28 - 30 °C

4: water; lithium chloride / ISOPROPYLAMIDE / 12 - 14 h / 113 - 115 °C

With water; sodium ethanolate; triethylamine; lithium chloride; palladium diacetate; 1,2-bis-(diphenylphosphino)ethane; lithium bromide; In ISOPROPYLAMIDE; toluene;

Reference yield:

: 953081-38-4
C₁₀H₉ClF₂O

: 953083-87-9
C₁₈H₂₁F₅N₂O₃

Guidance literature:: Multi-step reaction with 5 steps

1: sodium hydroxide / water; toluene / 4 h / 20 °C

2: sodium ethanolate / palladium diacetate; 1,2-bis-(diphenylphosphino)ethane / toluene / 6.25 - 10.25 h / 20 - 25 °C

3: triethylamine / toluene / 0.5 h / 3 °C

4: lithium bromide / ISOPROPYLAMIDE / 13 h / 28 - 30 °C

5: water; lithium chloride / ISOPROPYLAMIDE / 12 - 14 h / 113 - 115 °C

With sodium hydroxide; water; sodium ethanolate; triethylamine; lithium chloride; palladium diacetate; 1,2-bis-(diphenylphosphino)ethane; lithium bromide; In ISOPROPYLAMIDE; water; toluene;