(E)-4'-methyl-3-styrylflavone

Base Information

• Chemical Name: (E)-4'-methyl-3-styrylflavone
• CAS No.: 1373355-46-4
• Molecular Formula: C₂₄H₁₈O₂
• Molecular Weight: 338.406
• Mol file: 1373355-46-4.mol

Synonyms:(E)-4'-methyl-3-styrylflavone

Chemical Property of (E)-4'-methyl-3-styrylflavone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-4'-methyl-3-styrylflavone

There total 2 articles about (E)-4'-methyl-3-styrylflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 3-bromo-2-(4-methylphenyl)-4H-chromen-4-one → (E)-4'-methyl-3-styrylflavone (1373355-46-4)

Guidance literature:

With tetrabutylammomium bromide; palladium diacetate; potassium carbonate; In N,N-dimethyl-formamide; Inert atmosphere; Microwave irradiation;

DOI:10.1055/s-0031-1290355

Reference yield:

4'-methylflavone (41255-30-5) → (E)-4'-methyl-3-styrylflavone (1373355-46-4)

Guidance literature:

Multi-step reaction with 2 steps

1: N-Bromosuccinimide; pyridine / tetrachloromethane / Heating

2: potassium carbonate; potassium chloride; tetrabutylammomium bromide; palladium diacetate / N,N-dimethyl-formamide / 0.83 h / 110 °C / Inert atmosphere

With pyridine; N-Bromosuccinimide; potassium chloride; tetrabutylammomium bromide; palladium diacetate; potassium carbonate; In tetrachloromethane; N,N-dimethyl-formamide; 2: |Heck Reaction;

DOI:10.3998/ark.5550190.0013.519

Reference yield: 45.0%

(E)-4'-methyl-3-styrylflavone (1373355-46-4) → C24H16O2 (1373355-50-0)

Guidance literature:

With iodine; In 1,2,4-Trichlorobenzene; UV-irradiation;

DOI:10.1055/s-0031-1290355

upstream raw materials:

styrene

4'-methylflavone

Downstream raw materials:

C₂₄H₁₆O₂