meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine

Base Information

• Chemical Name: meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine
• CAS No.: 111086-58-9
• Molecular Formula: C₁₄H₁₂Cl₄N₂O₂
• Molecular Weight: 382.073
• Mol file: 111086-58-9.mol

Synonyms:meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine

Chemical Property of meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine

There total 2 articles about meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

(1R,2S)/(1S,2R)-1,2-bis(2,6-dichloro-4-methoxyphenyl)ethylenediamine (83363-98-8) → meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine (111086-58-9)

Guidance literature:

With hydrogen bromide; for 48h; Heating;

DOI:10.1021/jm00396a012

Reference yield:

C30H24Cl4N2O4 (111086-76-1) → meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine (111086-58-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 79 percent / aq. H₂SO₄

2: 50 percent / aq. HBr / 48 h / Heating

With sulfuric acid; hydrogen bromide;

DOI:10.1021/jm00396a012

Reference yield: 45.0%

meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine (111086-58-9) → meso-1,2-bis(2,6-dichloro-4-hydroxy<3,5-2H2>phenyl)ethylenediamine (143707-46-4)

Guidance literature:

With sulfuric acid-d2; In water-d2; at 68 ℃; for 3.5h;

DOI:10.1021/jm00101a027

upstream raw materials:

(1R,2S)/(1S,2R)-1,2-bis(2,6-dichloro-4-methoxyphenyl)ethylenediamine

C₃₀H₂₄Cl₄N₂O₄

Downstream raw materials:

meso-1,2-bis(2,6-dichloro-4-hydroxy<3,5-2H2>phenyl)ethylenediamine