2,3,4,5,6-Pentafluoro-benzenesulfonic acid (1S,8S,9R)-(4-aza-tricyclo[6.2.1.0^2,7]undeca-2,4,6-trien-9-yl) ester

Base Information

• Chemical Name: 2,3,4,5,6-Pentafluoro-benzenesulfonic acid (1S,8S,9R)-(4-aza-tricyclo[6.2.1.0^2,7]undeca-2,4,6-trien-9-yl) ester
• CAS No.: 90343-68-3
• Molecular Formula: C₁₆H₁₀F₅NO₃S
• Molecular Weight: 391.318

Synonyms:2,3,4,5,6-Pentafluoro-benzenesulfonic acid (1S,8S,9R)-(4-aza-tricyclo[6.2.1.0^2,7]undeca-2,4,6-trien-9-yl) ester

Chemical Property of 2,3,4,5,6-Pentafluoro-benzenesulfonic acid (1S,8S,9R)-(4-aza-tricyclo[6.2.1.0^2,7]undeca-2,4,6-trien-9-yl) ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4,5,6-Pentafluoro-benzenesulfonic acid (1S,8S,9R)-(4-aza-tricyclo[6.2.1.0^2,7]undeca-2,4,6-trien-9-yl) ester

There total 2 articles about 2,3,4,5,6-Pentafluoro-benzenesulfonic acid (1S,8S,9R)-(4-aza-tricyclo[6.2.1.0^2,7]undeca-2,4,6-trien-9-yl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5,8-Methano-5,6,7,8-tetrahydroisoquinolin-6-one (90343-75-2) → 2,3,4,5,6-Pentafluoro-benzenesulfonic acid (1S,8S,9R)-(4-aza-tricyclo[6.2.1.02,7]undeca-2,4,6-trien-9-yl) ester (90343-68-3)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄

2: 10.7 percent / n-butyllithium / tetrahydrofuran; hexane / 1) 0,5 h, 0 deg C, 2) 30 min

With lithium aluminium tetrahydride; n-butyllithium; In tetrahydrofuran; hexane;

DOI:10.1021/jo00188a003

Reference yield:

1,3-Dichloro-5,8-dihydro-5,8-methanoisoquinoline (90343-65-0) → 2,3,4,5,6-Pentafluoro-benzenesulfonic acid (1S,8S,9R)-(4-aza-tricyclo[6.2.1.02,7]undeca-2,4,6-trien-9-yl) ester (90343-68-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) diborane- dimethylsulfide complex, aqueous NaOH, 30percent H₂O₂, 2) H₂

2: 10.7 percent / n-butyllithium / tetrahydrofuran; hexane / 1) 0,5 h, 0 deg C, 2) 30 min

With sodium hydroxide; n-butyllithium; diborane-dimethylsulfide complex; hydrogen; dihydrogen peroxide; In tetrahydrofuran; hexane;

DOI:10.1021/jo00188a003

Reference yield: 90.1%

2,3,4,5,6-Pentafluoro-benzenesulfonic acid (1S,8S,9R)-(4-aza-tricyclo[6.2.1.02,7]undeca-2,4,6-trien-9-yl) ester (90343-68-3) → 2,3,4,5,6-Pentafluoro-benzenesulfonic acid (1S,8S,9R)-4-oxy-4-aza-tricyclo[6.2.1.02,7]undeca-2,4,6-trien-9-yl ester (90343-69-4)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In chloroform; for 4h; Ambient temperature;

DOI:10.1021/jo00188a003

upstream raw materials:

5,8-Methano-5,6,7,8-tetrahydroisoquinolin-6-one

1,3-Dichloro-5,8-dihydro-5,8-methanoisoquinoline

Downstream raw materials:

2,3,4,5,6-Pentafluoro-benzenesulfonic acid (1S,8S,9R)-4-oxy-4-aza-tricyclo[6.2.1.0^2,7]undeca-2,4,6-trien-9-yl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 90343-68-3 2,3,4,5,6-Pentafluoro-benzenesulfonic acid (1S,8S,9R)-(4-aza-tricyclo[6.2.1.0^2,7]undeca-2,4,6-trien-9-yl) ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send