Technology Process of 2-(2-Hydroxy-2-phenylethyl)-2,5,5-trimethylpyrrolidine-1-yloxyl radical
There total 3 articles about 2-(2-Hydroxy-2-phenylethyl)-2,5,5-trimethylpyrrolidine-1-yloxyl radical which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
5,8,8-trimethyl-3-phenyl-2-oxa-1-azabicyclo<3,3>oct-3-ene;
With
edetate disodium; acetic acid; zinc;
In
ethanol;
at 60 ℃;
for 0.75h;
With
water; dihydrogen peroxide;
sodium tungstate;
In
methanol;
at 20 ℃;
for 24h;
DOI:10.1055/s-1999-3503
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: toluene / 110 °C
2.1: ethylenediamine tetraacetic acid disodium salt; AcOH; Zn / ethanol / 0.75 h / 60 °C
2.2: 68 percent / H2O2; H2O / Na2WO4 / methanol / 24 h / 20 °C
With
edetate disodium; acetic acid; zinc;
In
ethanol; toluene;
1.1: Cycloaddition / 2.1: Ring cleavage / 2.2: Oxidation;
DOI:10.1055/s-1999-3503
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: toluene / 110 °C
2.1: ethylenediamine tetraacetic acid disodium salt; AcOH; Zn / ethanol / 0.75 h / 60 °C
2.2: 68 percent / H2O2; H2O / Na2WO4 / methanol / 24 h / 20 °C
With
edetate disodium; acetic acid; zinc;
In
ethanol; toluene;
1.1: Cycloaddition / 2.1: Ring cleavage / 2.2: Oxidation;
DOI:10.1055/s-1999-3503
