(1R,4'S,5'S/1S,4'S,5'S)-2-(1-chloroethyl)-4-methoxymethyl-5-phenyl-2-oxazoline

Base Information

Chemical Name:(1R,4'S,5'S/1S,4'S,5'S)-2-(1-chloroethyl)-4-methoxymethyl-5-phenyl-2-oxazoline
CAS No.:406220-07-3
Molecular Formula:C₁₃H₁₆ClNO₂
Molecular Weight:253.729
Hs Code.:

Synonyms:(1R,4'S,5'S/1S,4'S,5'S)-2-(1-chloroethyl)-4-methoxymethyl-5-phenyl-2-oxazoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1R,4'S,5'S/1S,4'S,5'S)-2-(1-chloroethyl)-4-methoxymethyl-5-phenyl-2-oxazoline

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Technology Process of (1R,4'S,5'S/1S,4'S,5'S)-2-(1-chloroethyl)-4-methoxymethyl-5-phenyl-2-oxazoline

There total 1 articles about (1R,4'S,5'S/1S,4'S,5'S)-2-(1-chloroethyl)-4-methoxymethyl-5-phenyl-2-oxazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 51594-37-7
(4S,5S)-2-ethyl-4-hydroxymethyl-5-phenyl-2-oxazoline methyl ether

: 406220-07-3
(1R,4'S,5'S/1S,4'S,5'S)-2-(1-chloroethyl)-4-methoxymethyl-5-phenyl-2-oxazoline

Guidance literature:: With tert-butylhypochlorite;
DOI:10.1055/s-2001-18447

Reference yield: 75.0%

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 406220-07-3
(1R,4'S,5'S/1S,4'S,5'S)-2-(1-chloroethyl)-4-methoxymethyl-5-phenyl-2-oxazoline

: (4S,5S)-4-Methoxymethyl-2-(2-methyl-1-oxa-spiro[2.5]oct-2-yl)-5-phenyl-4,5-dihydro-oxazole

Guidance literature:: (1R,4'S,5'S/1S,4'S,5'S)-2-(1-chloroethyl)-4-methoxymethyl-5-phenyl-2-oxazoline; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.333333h;

cyclohexanone; In tetrahydrofuran; at -78 ℃; for 1h;
DOI:10.1055/s-2001-18447

Reference yield: 75.0%

: 830-13-7
cyclododecanone

: 406220-07-3
(1R,4'S,5'S/1S,4'S,5'S)-2-(1-chloroethyl)-4-methoxymethyl-5-phenyl-2-oxazoline

: (4S,5S)-4-Methoxymethyl-2-(2-methyl-1-oxa-spiro[2.11]tetradec-2-yl)-5-phenyl-4,5-dihydro-oxazole

Guidance literature:: (1R,4'S,5'S/1S,4'S,5'S)-2-(1-chloroethyl)-4-methoxymethyl-5-phenyl-2-oxazoline; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.333333h;

cyclododecanone; In tetrahydrofuran; at -78 ℃; for 1h;
DOI:10.1055/s-2001-18447