(2R,4S,5S)-4,5-di[(tert-butyldimethylsilyl)oxy]-6,6-diethyloxy-1-(phenylsulfonyl)-2-methylheptane

Base Information

Chemical Name:(2R,4S,5S)-4,5-di[(tert-butyldimethylsilyl)oxy]-6,6-diethyloxy-1-(phenylsulfonyl)-2-methylheptane
CAS No.:335101-22-9
Molecular Formula:C₃₀H₅₈O₆SSi₂
Molecular Weight:603.024
Hs Code.:

Synonyms:(2R,4S,5S)-4,5-di[(tert-butyldimethylsilyl)oxy]-6,6-diethyloxy-1-(phenylsulfonyl)-2-methylheptane

Suppliers and Price of (2R,4S,5S)-4,5-di[(tert-butyldimethylsilyl)oxy]-6,6-diethyloxy-1-(phenylsulfonyl)-2-methylheptane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,4S,5S)-4,5-di[(tert-butyldimethylsilyl)oxy]-6,6-diethyloxy-1-(phenylsulfonyl)-2-methylheptane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,4S,5S)-4,5-di[(tert-butyldimethylsilyl)oxy]-6,6-diethyloxy-1-(phenylsulfonyl)-2-methylheptane

There total 4 articles about (2R,4S,5S)-4,5-di[(tert-butyldimethylsilyl)oxy]-6,6-diethyloxy-1-(phenylsulfonyl)-2-methylheptane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 335101-32-1
(2R,4S,5S)-4,5-di[(tert-butyldimethylsilyl)oxy]-2-methyl-6-oxy-heptaldehyde

: 335101-22-9
(2R,4S,5S)-4,5-di[(tert-butyldimethylsilyl)oxy]-6,6-diethyloxy-1-(phenylsulfonyl)-2-methylheptane

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / NaBH₄ / ethanol; CH₂Cl₂ / 1 h / -78 °C

2: triphenylphosphine; imidazole; I₂ / toluene / 1 h / 0 °C

3: dimethylformamide / 12 h

4: 64 percent / p-toluene sulfonic acid / ethanol / 1.5 h / Heating

With 1H-imidazole; sodium tetrahydroborate; iodine; toluene-4-sulfonic acid; triphenylphosphine; In ethanol; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1016/S0040-4020(02)00059-5

Reference yield:

: 335101-34-3
(2R,4S,5S)-4,5-di[(tert-butyldimethylsilyl)oxy]-1-hydroxy-2-methylheptan-6-one

: 335101-22-9
(2R,4S,5S)-4,5-di[(tert-butyldimethylsilyl)oxy]-6,6-diethyloxy-1-(phenylsulfonyl)-2-methylheptane

Guidance literature:: Multi-step reaction with 3 steps

1: triphenylphosphine; imidazole; I₂ / toluene / 1 h / 0 °C

2: dimethylformamide / 12 h

3: 64 percent / p-toluene sulfonic acid / ethanol / 1.5 h / Heating

With 1H-imidazole; iodine; toluene-4-sulfonic acid; triphenylphosphine; In ethanol; N,N-dimethyl-formamide; toluene;
DOI:10.1016/S0040-4020(02)00059-5

Reference yield:

: 873-55-2
sodium benzenesulfonate

: 335101-22-9
(2R,4S,5S)-4,5-di[(tert-butyldimethylsilyl)oxy]-6,6-diethyloxy-1-(phenylsulfonyl)-2-methylheptane

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylformamide / 12 h

2: 64 percent / p-toluene sulfonic acid / ethanol / 1.5 h / Heating

With toluene-4-sulfonic acid; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(02)00059-5