Technology Process of C20H21FN4O5
There total 6 articles about C20H21FN4O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: pyridine / dichloromethane / 0.5 h
2.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.5 h
3.1: palladium on activated charcoal; hydrogen / methanol / 1 h / 20 °C / 760.05 Torr
4.1: diethyl methoxy borane; ytterbium(III) triflate / isopropyl alcohol / 1.5 h / 80 °C
4.2: 1 h / 80 °C
With
pyridine; palladium on activated charcoal; diethyl methoxy borane; hydrogen; N-ethyl-N,N-diisopropylamine; ytterbium(III) triflate;
In
methanol; dichloromethane; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1021/ml1002458
- Guidance literature:
-
C12H16FN3O3; (S)-(+)-3-(2-cyanophenoxy)-1,2-epoxypropane;
With
diethyl methoxy borane; ytterbium(III) triflate;
In
isopropyl alcohol;
at 80 ℃;
for 1.5h;
With
water; lithium hydroxide;
In
isopropyl alcohol;
at 80 ℃;
for 1h;
DOI:10.1021/ml1002458
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.5 h
2.1: palladium on activated charcoal; hydrogen / methanol / 1 h / 20 °C / 760.05 Torr
3.1: diethyl methoxy borane; ytterbium(III) triflate / isopropyl alcohol / 1.5 h / 80 °C
3.2: 1 h / 80 °C
With
palladium on activated charcoal; diethyl methoxy borane; hydrogen; N-ethyl-N,N-diisopropylamine; ytterbium(III) triflate;
In
methanol; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1021/ml1002458
