Technology Process of 13,14,16,17-tetrahydro-5,8-epithiodibenzo
cyclotridecen-15-one
There total 1 articles about 13,14,16,17-tetrahydro-5,8-epithiodibenzocyclotridecen-15-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 9 steps
1: 1.95 g / 1.41 M potassium hydroxide / diethyl ether; methanol / 4 h / Ambient temperature
2: 297 mg / 1,8-diazabicyclo<5.4.0>undec-7-ene, silver nitrate / CH2Cl2 / 30 h / 40 °C
3: 85 percent / tributyltin hydride
4: 80 percent / tributyltin hydride, acetic acid, tetrakis(triphenylphosphine)palladium(0) / benzene / Ambient temperature
5: 92 percent / potassium fluoride dihydrate / dimethylformamide / 1 h / Ambient temperature
6: 76.8 percent / anhydrous copper acetate / pyridine; diethyl ether / 0.5 h / 50 °C
7: 93.6 percent / sodium borohydride / ethanol / 0.17 h
8: 29.8 percent / sodium sulphide nonahydrate / methanol / 17 h / Heating
9: 186.3 mg / chromium trioxide / acetone; H2O; H2SO4 / 1 h / Ambient temperature
With
chromium(VI) oxide; sodium sulfide; potassium fluoride; potassium hydroxide; sodium tetrahydroborate; tetrakis(triphenylphosphine) palladium(0); tri-n-butyl-tin hydride; copper (I) acetate; silver nitrate; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
pyridine; methanol; diethyl ether; ethanol; dichloromethane; sulfuric acid; water; N,N-dimethyl-formamide; acetone; benzene;
- Guidance literature:
-
With
hydrogenchloride;
In
ethanol;
for 0.5h;
Heating;
